Anti-Claudin 16 [4C10]
Invented at A*STAR Accelerate Technologies Pte Ltd
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![Cos cells expressing exogenously expressed GFP-tagged Claudin-16 (left most pane) were immunolabelled using anti-Claudin 16 [4C10] (middle). A merge of both signals shows overlapping staining.](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/fa2e0f4b-ef31-4f94-a9cf-654aa1f6eb2f.png)
![Cos cells expressing exogenously expressed GFP-tagged Claudin-16 (left most pane) were immunolabelled using anti-Claudin 16 [4C10] (middle). A merge of both signals shows overlapping staining.](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/fa2e0f4b-ef31-4f94-a9cf-654aa1f6eb2f.png)
![Image thumbnail for Anti-Claudin 16 [4C10]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/fa2e0f4b-ef31-4f94-a9cf-654aa1f6eb2f.png)
| Catalogue Number | 152638 |
| Applications | IF |
| Antigen/Gene or Protein Targets | Claudin-16 |
| Synonyms | CLD16 |
| Reactivity | Human |
| Relevance | Claudin-16 (CLD16) is component of the tight junction in kidney. It is exclusively expressed in the thick ascending of limb of Henle (TALH). This is involved in the parcellular transport of Mg2+ in the TALH. Mutations in claudin-16 have been implicated in the loss of Mg in the urine. Claudin16 antibody is raised using the extracellular loop 1 as an antigen. |
| Host | Mouse |
| Immunogen | CLD16-KLH peptide conjugate |
| Subclass | IgM |
| Myeloma Used | Sp2/0-Ag14 |
| Research Area | Cell Structure and Motility |
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