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Anti-Claudin 16 [4C10]

Info

Catalogue Number 152638
Applications IF
Antigen/Gene or Protein Targets Claudin-16
Synonyms CLD16
Reactivity Human
Relevance Claudin-16 (CLD16) is component of the tight junction in kidney. It is exclusively expressed in the thick ascending of limb of Henle (TALH). This is involved in the parcellular transport of Mg2+ in the TALH. Mutations in claudin-16 have been implicated in the loss of Mg in the urine. Claudin16 antibody is raised using the extracellular loop 1 as an antigen.
Host Mouse
Immunogen CLD16-KLH peptide conjugate
Subclass IgM
Myeloma Used Sp2/0-Ag14
Research Area Cell Structure and Motility

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