Anti-sCD40 (soluble) [T8P2G4*A6]
Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
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![Western blot was performed using anti-sCD40 (soluble) [T8P2G4*A6] applied to Jurkat cell lysates](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/1c76a8dc-a1c6-4abf-95f4-91ee101e82b9.png)
![Immunohistochemistry was performed on hepatocellular carcinoma using anti-sCD40 (soluble) [T8P2G4*A6].](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/bd8a1664-e826-4bd6-bb5d-e8d857759479.jpg)
![Immunohistochemical staining of human breast cancer shows using anti-sCD40 (soluble) [T8P2G4*A6]. Positive cytoplasmic staining is shown.](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/1cd393af-9a1f-492e-8f8d-a62d231dd188.jpg)
![Western blot was performed using anti-sCD40 (soluble) [T8P2G4*A6] applied to Jurkat cell lysates](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/1c76a8dc-a1c6-4abf-95f4-91ee101e82b9.png)
![Immunohistochemistry was performed on hepatocellular carcinoma using anti-sCD40 (soluble) [T8P2G4*A6].](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/bd8a1664-e826-4bd6-bb5d-e8d857759479.jpg)
![Immunohistochemical staining of human breast cancer shows using anti-sCD40 (soluble) [T8P2G4*A6]. Positive cytoplasmic staining is shown.](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/1cd393af-9a1f-492e-8f8d-a62d231dd188.jpg)
![Image thumbnail for Anti-sCD40 (soluble) [T8P2G4*A6]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/1c76a8dc-a1c6-4abf-95f4-91ee101e82b9.png)
![Image thumbnail for Anti-sCD40 (soluble) [T8P2G4*A6]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/bd8a1664-e826-4bd6-bb5d-e8d857759479.jpg)
![Image thumbnail for Anti-sCD40 (soluble) [T8P2G4*A6]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/1cd393af-9a1f-492e-8f8d-a62d231dd188.jpg)
| Catalogue Number | 152605 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40 soluble form) |
| Synonyms | CD40 Molecule; CD40L Receptor; TNFRSF5; CDW40; Bp50; Tumor Necrosis Factor Receptor Superfamily; Member; B Cell Surface Antigen CD40; CD40 Antigen; P50 |
| Reactivity | Human |
| Relevance | CD40 is a 48 kD type I glycoprotein and a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. |
| Host | Mouse |
| Immunogen | Ovalbumin-conjugated synthetic peptide RDPVCHPLGA (C-terminal sequence) |
| Positive Control | IHC - formalin-fixed, paraffin-embedded hepatocellular carcinoma sections; WB - Jurkat cell lysates |
| Subclass | IgG2b kappa |
| Molecular Weight (kDa) | 22 |
| Research Area | Cancer, Cell Signaling & Signal Transduction |
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