Anti-Alanyl-tRNA Synthetase [M6-P2E5]
Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
- Datasheet
- References (0)
- Inventor Info
Info
![Image for Anti-Alanyl-tRNA Synthetase [M6-P2E5]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/57f1c585-a77d-44eb-99fe-3dbdee2d8ef3.png)
![Immunohistochemistry of formalin-fixed, paraffin-embedded human colorectal cancer tissue using anti-Alanyl-tRNA Synthetase [M6-P2E5] showing strong cytoplasmic staining.](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/925c6d6f-6b31-495f-925a-1fea9473ea62.jpg)
![Figure. Immunohistochemistry was performed on normal colon mucosa (A) and primary colorectal tumour (B) using anti-anti-AARS antibody [M6-P2E5]. Cytoplasmic localisation of AARS is observed.](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/84b9745c-e9bb-4602-92fe-10543f35ea5c.jpg)
![Immunohistochemistry was performed on formalin-fixed, paraffin-embedded tissue sections. Strong cytoplasmic staining is observed in breast carcinoma using Anti-Alanyl-tRNA Synthetase [M6-P2E5]. Antigen retrieval step was required (microwave 10 min @ 950W in 0.01M sodium citrate. buffer, pH 6.0).](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/c1c6dcaa-b83e-425a-a483-57b07841303e.jpg)
![Microsatellite instability status of Anti-Alanyl-tRNA Synthetase intensity of expression in colorectal cancer using [M6-P2E5].](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/635d46f3-2b23-49b9-8cb8-3bc115a7415b.png)
![Image for Anti-Alanyl-tRNA Synthetase [M6-P2E5]](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/57f1c585-a77d-44eb-99fe-3dbdee2d8ef3.png)
![Immunohistochemistry of formalin-fixed, paraffin-embedded human colorectal cancer tissue using anti-Alanyl-tRNA Synthetase [M6-P2E5] showing strong cytoplasmic staining.](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/925c6d6f-6b31-495f-925a-1fea9473ea62.jpg)
![Figure. Immunohistochemistry was performed on normal colon mucosa (A) and primary colorectal tumour (B) using anti-anti-AARS antibody [M6-P2E5]. Cytoplasmic localisation of AARS is observed.](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/84b9745c-e9bb-4602-92fe-10543f35ea5c.jpg)
![Immunohistochemistry was performed on formalin-fixed, paraffin-embedded tissue sections. Strong cytoplasmic staining is observed in breast carcinoma using Anti-Alanyl-tRNA Synthetase [M6-P2E5]. Antigen retrieval step was required (microwave 10 min @ 950W in 0.01M sodium citrate. buffer, pH 6.0).](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/c1c6dcaa-b83e-425a-a483-57b07841303e.jpg)
![Microsatellite instability status of Anti-Alanyl-tRNA Synthetase intensity of expression in colorectal cancer using [M6-P2E5].](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/635d46f3-2b23-49b9-8cb8-3bc115a7415b.png)
![Image thumbnail for Anti-Alanyl-tRNA Synthetase [M6-P2E5]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/57f1c585-a77d-44eb-99fe-3dbdee2d8ef3.png)
![Image thumbnail for Anti-Alanyl-tRNA Synthetase [M6-P2E5]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/925c6d6f-6b31-495f-925a-1fea9473ea62.jpg)
![Image thumbnail for Anti-Alanyl-tRNA Synthetase [M6-P2E5]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/84b9745c-e9bb-4602-92fe-10543f35ea5c.jpg)
![Image thumbnail for Anti-Alanyl-tRNA Synthetase [M6-P2E5]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/c1c6dcaa-b83e-425a-a483-57b07841303e.jpg)
![Image thumbnail for Anti-Alanyl-tRNA Synthetase [M6-P2E5]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/635d46f3-2b23-49b9-8cb8-3bc115a7415b.png)
| Catalogue Number | 152601 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Alanyl-tRNA Synthetase (AARS) |
| Reactivity | Human |
| Relevance | The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity with the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific amino acids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. |
| Host | Mouse |
| Immunogen | Peptide – TSFAQLRLGD (amino acid 956-965) |
| Positive Control | Western Blot - Hela cell lysates; IHC - Human breast cancer tissue |
| Subclass | IgG1 kappa |
| Molecular Weight (kDa) | 110 |
| Notes | Please note for IHC antigen retrieval is required: ,icrowave 20 min @ 800W in 10 mM citrate buffer, pH 6.0 |
| Research Area | Epigenetics & Nuclear Signalling |
References
There are 0 reference entries for this reagent.
References: 0 entry
There is no reference for this reagent yet, feel free to use the button below to suggest one.
Add a reference
References: 0 entry
There is no reference for this reagent yet, feel free to use the button below to suggest one.
Add a reference
