#152601

Anti-Alanyl-tRNA Synthetase [M6-P2E5]

Cat. #152601

Anti-Alanyl-tRNA Synthetase [M6-P2E5]

Cat. #: 152601

Unit size: 100 ug

Availability: 10-12 weeks

Target: Alanyl-tRNA Synthetase (AARS)

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Alanyl-tRNA Synthetase [M6-P2E5]
  • Clone: M6-P2E5
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 110
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity with the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific amino acids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
  • Immunogen: Peptide Sequence – TSFAQLRLGD (amino acid 956-965)
  • Isotype: IgG1 kappa
  • Recommended controls: Western Blot - Hela cell lysates; IHC - Human breast cancer tissue

Target Details

  • Target: Alanyl-tRNA Synthetase (AARS)
  • Molecular weight: 110
  • Target background: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity with the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific amino acids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C