Anti-MSP1 Blocks 6 to 16 [9.7]

Info

Review this reagent

Applications	N/A
Antigen/Gene or Protein Targets	MSP-1 (MAD20 type)
Reactivity	Plasmodium
Relevance	Malaria continues to be a significant health problem in India. Several of the intended Plasmodium falciparum vaccine candidate antigens are highly polymorphic. The genetic diversity of P. falciparum merozoite surface protein-1 (MSP-1) has been extensively studied from various parts of the world. The block 2 region includes three allele families: K1, MAD20, and RO33. Characterization of antigenic diversity in vaccine candidate antigens are valuable for future vaccine trials as well as understanding the population dynamics of P. falciparum parasites.
Host	Mouse
Immunogen	Schizonts of the PB1 isolate
Subclass	IgG1
Myeloma Used	P3/NS1/1-Ag4.1
Notes	Recognises an epitope in the MAD20 allelic type of MSP-1 of P. falciparum. Target is a conformational epitope within Blocks 6 to 16. UK Biosafety level: 1
Research Area	Parasitology

References: 1 entry

McBride et al. 1984. Trans R Soc Trop Med Hyg. 78(1):32-4. PMID: 6200967.

View  

Add a reference

References: 1 entry

McBride et al. 1984. Trans R Soc Trop Med Hyg. 78(1):32-4. PMID: 6200967.

View  

Add a reference

References: 1 entry

McBride et al. 1984. Trans R Soc Trop Med Hyg. 78(1):32-4. PMID: 6200967.

View  

Add a reference

Have you used this reagent? Share your experience by submitting a review and help your fellow scientists.

Review this reagent

This reagent does not have any reviews at the moment.