Anti-MSP1 Blocks 6 to 16 [9.7]
- Datasheet
- References (1)
- Inventor Info
Info
| Applications | N/A |
| Antigen/Gene or Protein Targets | MSP-1 (MAD20 type) |
| Reactivity | Plasmodium |
| Relevance | Malaria continues to be a significant health problem in India. Several of the intended Plasmodium falciparum vaccine candidate antigens are highly polymorphic. The genetic diversity of P. falciparum merozoite surface protein-1 (MSP-1) has been extensively studied from various parts of the world. The block 2 region includes three allele families: K1, MAD20, and RO33. Characterization of antigenic diversity in vaccine candidate antigens are valuable for future vaccine trials as well as understanding the population dynamics of P. falciparum parasites. |
| Host | Mouse |
| Immunogen | Schizonts of the PB1 isolate |
| Subclass | IgG1 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Notes |
Recognises an epitope in the MAD20 allelic type of MSP-1 of P. falciparum. Target is a conformational epitope within Blocks 6 to 16. UK Biosafety level: 1 |
| Research Area | Parasitology |
