- Datasheet
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- Inventor Info
Info
Applications | N/A |
Antigen/Gene or Protein Targets | MSP-1 (MAD20 type) |
Reactivity | Plasmodium |
Relevance | Malaria continues to be a significant health problem in India. Several of the intended Plasmodium falciparum vaccine candidate antigens are highly polymorphic. The genetic diversity of P. falciparum merozoite surface protein-1 (MSP-1) has been extensively studied from various parts of the world. The block 2 region includes three allele families: K1, MAD20, and RO33. Characterization of antigenic diversity in vaccine candidate antigens are valuable for future vaccine trials as well as understanding the population dynamics of P. falciparum parasites. |
Host | Mouse |
Immunogen | Schizonts of the PB1 isolate |
Subclass | IgG1 |
Myeloma Used | P3/NS1/1-Ag4.1 |
Notes |
Recognises an epitope in the MAD20 allelic type of MSP-1 of P. falciparum. Target is a conformational epitope within Blocks 6 to 16. UK Biosafety level: 1 |
Research Area | Parasitology |