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Anti-MSP1 Blocks 6 to 16 [9.7]

Info

Applications N/A
Antigen/Gene or Protein Targets MSP-1 (MAD20 type)
Reactivity Plasmodium
Relevance Malaria continues to be a significant health problem in India. Several of the intended Plasmodium falciparum vaccine candidate antigens are highly polymorphic. The genetic diversity of P. falciparum merozoite surface protein-1 (MSP-1) has been extensively studied from various parts of the world. The block 2 region includes three allele families: K1, MAD20, and RO33. Characterization of antigenic diversity in vaccine candidate antigens are valuable for future vaccine trials as well as understanding the population dynamics of P. falciparum parasites.
Host Mouse
Immunogen Schizonts of the PB1 isolate
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Notes Recognises an epitope in the MAD20 allelic type of MSP-1 of P. falciparum. Target is a conformational epitope within Blocks 6 to 16.
UK Biosafety level: 1
Research Area Parasitology

References: 1 entry

McBride et al. 1984. Trans R Soc Trop Med Hyg. 78(1):32-4. PMID: 6200967.


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References: 1 entry

McBride et al. 1984. Trans R Soc Trop Med Hyg. 78(1):32-4. PMID: 6200967.


Add a reference

References: 1 entry

McBride et al. 1984. Trans R Soc Trop Med Hyg. 78(1):32-4. PMID: 6200967.


Add a reference


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