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Anti-MSP1 Blocks 6 to 16 [9.2]

Info

Applications N/A
Antigen/Gene or Protein Targets MSP-1 (MAD20 type)
Reactivity Plasmodium
Relevance In considering methods for immunological control of Plasmodium falciparum malaria it is essential to know more about antigenic diversity within and between natural populations of the parasite from major endemic areas. A successful malaria vaccine would stimulate an individual's immune system to respond to the malaria parasite and prevent serious clinical disease. Many different groups are currently developing potential vaccines. Several candidates are based on a protein called MSP1 (merozoite surface protein 1) which is found on the surface of the blood stage form of the malaria parasite.
Host Mouse
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Notes Recognises the MAD20 form of MSP-1, binding to an allele specific epitope within the 1078-NSLNNPHN to RVSGSSGS-1251 sequence within the Block6-16 region
UK Biosafety level: 1
Research Area Parasitology

References: 1 entry

McBride et al. 1985. J Exp Med. 161(1):160-80. PMID: 2578540.


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References: 1 entry

McBride et al. 1985. J Exp Med. 161(1):160-80. PMID: 2578540.


Add a reference

References: 1 entry

McBride et al. 1985. J Exp Med. 161(1):160-80. PMID: 2578540.


Add a reference


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