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KARPAS 417 Cell Line

Invented by Abraham Karpas

Info

Antigen/Gene or Protein Targets Human multiple myeloma
Host Human
Tissue Blood
Disease Keywords Cancer; haemotology; leukaemia
Relevance The KARPAS 417 cell line is a Human Multiple Myeloma cell line useful in oncology research.
Production Details Established from the peripheral blood of a 56 year-old male diagnosed with multiple myeloma.
Research Area Cancer, Drug Discovery & Development
Growth/Phenotype Keywords Single round to polymorphic cells growing in suspension; Complex translocations; Secretes IgGks
Recommended Growing Conditions Maintain cultures between 0.5 - 2 x 1000,000 cells/ml; 5% CO2; 37°C. Doubling time approximately 60 hours. Split saturated culture 1:2 every 2-4 days. Round to polymorhpic cells growing singly or in small clusters in suspension. Culture medium: RPMI 1640 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).
Cellosaurus ID CVCL_2542

References

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References: 1 entry

Karpas et al. 2001. Proc Natl Acad Sci U S A. 98(4):1799-804. PMID: 11172031.


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References: 1 entry

Karpas et al. 2001. Proc Natl Acad Sci U S A. 98(4):1799-804. PMID: 11172031.


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