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Anti-HSV VP21/VP22a [LP13]

Info

Applications IHC IF IP WB
Antigen/Gene or Protein Targets Herpes Simplex Virus VP21/VP22a (scaffold)
Reactivity Virus
Relevance Herpes simplex virus (HSV) virions are multilayered, and their assembly requires several steps (reviewed in references 21 and 59). The double-stranded DNA viral genome is enclosed within a well-ordered protein capsid. A more amorphous layer of proteins referred to as the tegument surrounds the capsid. Lying outside of the tegument, the outermost layer of the virion consists of a lipid envelope containing viral glycoproteins. Herpes simplex virus type 1 (HSV-1) capsids are initially assembled with an internal protein scaffold. The scaffold proteins, encoded by overlapping in-frame UL26 and UL26.5 transcripts, are essential for formation and efficient maturation of capsids.
Host Mouse
Immunogen Herpes Simplex Virus Type-1 VP21/VP22a scaffold protein
Subclass IgG2a
Notes Works well for immunofluorescence (IF) on fixed specimens and for immunoprecipitiation (IP) on triton solubilised samples. Can be used to detect protein by Western blot.
Research Area Virology

References

There are 1 reference entries for this reagent.

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References: 1 entry

McClelland et al. 2002. J Virol. 76(15):7407-17. PMID: 12097553.


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References: 1 entry

McClelland et al. 2002. J Virol. 76(15):7407-17. PMID: 12097553.


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