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Anti-IL-9R [AH9R2]

Info

Applications FACS IP WB
Antigen/Gene or Protein Targets IL-9R
Reactivity Human
Relevance IL-9 is a potent, T cell-derived, T cell growth factor which can also enhance mast cell activity and IL-3- or IL-4- dependent proliferation of bone marrow-derived mast cells. IL-9 synergizes with erythropoietin to promote erythroid colony formation. IL-9 has also been reported to protect human T cells from apoptosis induced by IL-2 withdrawal. IL-9 is upregulated in human eosinophils by TNF-α and IL1-β. IL-9 has been reported to downregulate the oxidative burst in activated human alveolar macrophages and induce TGF-β production. The recently characterized Th-9 helper cell lineage is characterized by the production of IL-9. The MH9A4 antibody reacts with human IL-9. The MH9A4 antibody can neutralize the bioactivity of natural or recombinant IL-9.
Host Mouse
Subclass IgG2b
Research Area Apoptosis and Programmed Cell Death, Cancer, Immunology

References: 1 entry

Demoulin et al. 1996. Mol Cell Biol. 16(9):4710-6. PMID: 8756628.


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References: 1 entry

Demoulin et al. 1996. Mol Cell Biol. 16(9):4710-6. PMID: 8756628.


Add a reference

References: 1 entry

Demoulin et al. 1996. Mol Cell Biol. 16(9):4710-6. PMID: 8756628.


Add a reference


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