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Anti-CD25 [PC61 5.3]

Info

Applications FACS IHC IP
Antigen/Gene or Protein Targets CD25
Synonyms Interleukin 2 Receptor Subunit Alpha; IL-2 Receptor Subunit Alpha; IL-2R Subunit Alpha; TAC Antigen; P55; Insulin-Dependent Diabetes Mellitus 10; CD25 Antigen
Reactivity Mouse
Relevance CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor α chain. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ T cells termed T regulatory cells. CD25 associates with the IL-2 receptor β (CD122) and common γ chains (CD132) to form the high affinity IL-2R complex.
Host Rat
Subclass IgG1
Research Area Immunology, Protein Degradation

References

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References: 1 entry

Lowenthal et al. 1985. J Immunol. 135(6):3988-94. PMID: 3934270.


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References: 1 entry

Lowenthal et al. 1985. J Immunol. 135(6):3988-94. PMID: 3934270.


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