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Catalogue Number
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152358 |
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Applications
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FACS
IHC
IP
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Antigen/Gene or Protein Targets
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CD25
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Synonyms
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Interleukin 2 Receptor Subunit Alpha; IL-2 Receptor Subunit Alpha; IL-2R Subunit Alpha; TAC Antigen; P55; Insulin-Dependent Diabetes Mellitus 10; CD25 Antigen
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Reactivity
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Mouse
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Relevance
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CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor α chain. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ T cells termed T regulatory cells. CD25 associates with the IL-2 receptor β (CD122) and common γ chains (CD132) to form the high affinity IL-2R complex.
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Host
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Rat
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Subclass
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IgG1
|
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Research Area
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Immunology, Protein Degradation
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