Anti-CD19 [6D5]
Invented by Douglas Fearon , Anthony de Fougerolles
Invented at University of Cambridge
- Datasheet
- References (2)
- Inventor Info
Info
| Applications | FACS IHC IP WB |
| Antigen/Gene or Protein Targets | CD19 |
| Synonyms | CD19 Molecule; B-Lymphocyte Surface Antigen B4; T-Cell Surface Antigen Leu-12; Differentiation Antigen CD19; CD19 Antigen; CVID3; B4 |
| Reactivity | Mouse |
| Relevance | CD19 a cell surface molecule which assembles with the antigen receptor of B lymphocytes. A critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation. Ligation increases intracellular calcium levels and decreases the threshold for antigen receptor signalling. Germinal center formation is significantly reduced in CD19-deficient mice. |
| Host | Rat |
| Immunogen | Human K562 cell line transfected with murine CD19 |
| Research Area | Cancer, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology |
References: 2 entries
De Jesus et al. 2009. J Immunol. 183(6):3885-94. PMID: 19684080.
Jégou et al. 2007. J Immunol. 178(5):3323-31. PMID: 17312184.
Add a reference
References: 2 entries
De Jesus et al. 2009. J Immunol. 183(6):3885-94. PMID: 19684080.
Jégou et al. 2007. J Immunol. 178(5):3323-31. PMID: 17312184.
Add a reference
Inventor Information
Inventors
|
Douglas Fearon |
|
|
Anthony de Fougerolles |
