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Anti-CD19 [6D5]

Invented by Douglas Fearon, Anthony de Fougerolles

Info

Applications FACS IHC IP WB
Antigen/Gene or Protein Targets CD19
Synonyms CD19 Molecule; B-Lymphocyte Surface Antigen B4; T-Cell Surface Antigen Leu-12; Differentiation Antigen CD19; CD19 Antigen; CVID3; B4
Reactivity Mouse
Relevance CD19 a cell surface molecule which assembles with the antigen receptor of B lymphocytes. A critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation. Ligation increases intracellular calcium levels and decreases the threshold for antigen receptor signalling. Germinal center formation is significantly reduced in CD19-deficient mice.
Host Rat
Immunogen Human K562 cell line transfected with murine CD19
Research Area Cancer, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology

References: 2 entries

De Jesus et al. 2009. J Immunol. 183(6):3885-94. PMID: 19684080.

Jégou et al. 2007. J Immunol. 178(5):3323-31. PMID: 17312184.


Add a reference

References: 2 entries

De Jesus et al. 2009. J Immunol. 183(6):3885-94. PMID: 19684080.

Jégou et al. 2007. J Immunol. 178(5):3323-31. PMID: 17312184.


Add a reference

References: 2 entries

De Jesus et al. 2009. J Immunol. 183(6):3885-94. PMID: 19684080.

Jégou et al. 2007. J Immunol. 178(5):3323-31. PMID: 17312184.


Add a reference


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