Anti-ERCC3 [15TF2-1B3]
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Info
| Applications | ELISA IHC IF WB |
| Antigen/Gene or Protein Targets | XPB ((Xeroderma pigmentosum group B) |
| Reactivity | N/A |
| Relevance | ERCC3 or XBP is a ATP-dependent DNA helicase that functions in nucleotide excision repair (NEF) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The encoded protein is a subunit of basal transcription factor 2 (TFIIH). ERCC3 acts by opening DNA either around the RNA transcription start site or the DNA damage. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. |
| Host | Mouse |
| Immunogen | Recomb prot |
| Subclass | IgG1 kappa |
| Notes | Available in 100ul unit |
| Research Area | DNA Damage and Repair, Epigenetics & Nuclear Signalling |
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