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Anti-ERCC3 [15TF2-1B3]

Info

Applications ELISA IHC IF WB
Antigen/Gene or Protein Targets  XPB ((Xeroderma pigmentosum group B) 
Reactivity N/A
Relevance ERCC3 or XBP is a ATP-dependent DNA helicase that functions in nucleotide excision repair (NEF) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The encoded protein is a subunit of basal transcription factor 2 (TFIIH). ERCC3 acts by opening DNA either around the RNA transcription start site or the DNA damage. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy.
Host Mouse
Immunogen Recomb prot
Subclass IgG1 kappa
Notes Available in 100ul unit
Research Area DNA Damage and Repair, Epigenetics & Nuclear Signalling

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