Anti-TAF15 [7TA-2B11]
- Datasheet
- References (4)
- Inventor Info
Info
| Applications | ELISA IF IP WB |
| Antigen/Gene or Protein Targets | TAF15/TAFII 68 |
| Reactivity | Human |
| Relevance | TAF15 is a member of the TET family of RNA-binding proteins. It plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. |
| Host | Mouse |
| Immunogen | Synthetic peptide RDYGPRTDADSESDNSD (amino acids 213-229) coupled to ovalbumin |
| Subclass | IgG1 kappa |
| Notes |
Available in 100ul units Recommended dilution: 1/500-1/5000 |
| Research Area | Epigenetics & Nuclear Signalling |
References: 4 entries
Bertolotti et al. 1998. Mol Cell Biol. 18(3):1489-97. PMID: 9488465.
EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.
Europe PMC ID: 9488465
Bertolotti et al. 1996. EMBO J. 15(18):5022-31. PMID: 8890175.
hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II.
Europe PMC ID: 8890175
Add a reference
References: 4 entries
Bertolotti et al. 1998. Mol Cell Biol. 18(3):1489-97. PMID: 9488465.
EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.
Bertolotti et al. 1996. EMBO J. 15(18):5022-31. PMID: 8890175.
hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II.
Add a reference
