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Anti-CCNL1 [3CY-2F10]

Info

Applications ELISA IHC IF WB
Antigen/Gene or Protein Targets  Cyclin L1 
Synonyms Cyclin L1; Cyclin-L; Cyclin L Ania-6a; Cyclin L Gamma; PRO1073; Ania-6a; ANIA6A; BM-001
Reactivity Human, Mouse and Rat
Relevance Monoclonal Anti-Cyclin L1, clone 3CY-2F10, recognises human, mouse and rat Cyclin L1. Cyclin L1 is a Transcriptional regulator which participates in regulating the pre-mRNA splicing process. It appears to be involved in the regulation of RNA polymerase II (pol II). It functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. Cyclin L1 is a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). it is inhibited by the CDK-specific inhibitor p21.
Host Mouse
Immunogen (C)SKHHGGSRSGHGRHRR (synthetic peptide corresponding to aa 511 to 526 of human Cyclin L1)
Subclass IgG2a kappa
Notes Available in 100ul unit as ascites.

Recommended dilutions: 1/500-1/5000
Research Area Cancer, Cell Cycle, Epigenetics & Nuclear Signalling

References: 1 entry

Muller et al. 2006. Br J Cancer. 94(7):1041-4. PMID: 16598186.


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References: 1 entry

Muller et al. 2006. Br J Cancer. 94(7):1041-4. PMID: 16598186.


Add a reference

References: 1 entry

Muller et al. 2006. Br J Cancer. 94(7):1041-4. PMID: 16598186.


Add a reference


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