Anti-Cytochrome P450 4Z1 [N7-P2G5*D8]
Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
- Datasheet
- References (4)
- Inventor Info
Info
![Image for Anti-Cytochrome P450 4Z1 [N7-P2G5*D8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/211778ce-4405-45e5-888d-353326b7e3d9.jpg)
![Image for Anti-Cytochrome P450 4Z1 [N7-P2G5*D8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/49e94ab8-d8a0-4f94-9b17-8409c2ca6d66.jpg)
![Immunohistochemistry was performed on formalin-fixed, paraffin-embedded normal, primary and metastatic colorectal tumour tissue sections using neat culture supernatants of anti-CYP4Z1 [N7-P2G5*D8].
The photomicrographs show negative staining of anti-CYP4Z1 [N7-P2G5*D8] in normal colon mucosa and moderate and weak staining in primary colorectal and lymph node metastatic tumours respectively. Cytoplasmic localisation of CYP4Z1 is observed.](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/8f335296-9492-4803-8a62-f43474474c04.jpg)
![Image for Anti-Cytochrome P450 4Z1 [N7-P2G5*D8]](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/211778ce-4405-45e5-888d-353326b7e3d9.jpg)
![Image for Anti-Cytochrome P450 4Z1 [N7-P2G5*D8]](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/49e94ab8-d8a0-4f94-9b17-8409c2ca6d66.jpg)
![Immunohistochemistry was performed on formalin-fixed, paraffin-embedded normal, primary and metastatic colorectal tumour tissue sections using neat culture supernatants of anti-CYP4Z1 [N7-P2G5*D8].
The photomicrographs show negative staining of anti-CYP4Z1 [N7-P2G5*D8] in normal colon mucosa and moderate and weak staining in primary colorectal and lymph node metastatic tumours respectively. Cytoplasmic localisation of CYP4Z1 is observed.](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/8f335296-9492-4803-8a62-f43474474c04.jpg)
![Image thumbnail for Anti-Cytochrome P450 4Z1 [N7-P2G5*D8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/211778ce-4405-45e5-888d-353326b7e3d9.jpg)
![Image thumbnail for Anti-Cytochrome P450 4Z1 [N7-P2G5*D8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/49e94ab8-d8a0-4f94-9b17-8409c2ca6d66.jpg)
![Image thumbnail for Anti-Cytochrome P450 4Z1 [N7-P2G5*D8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/8f335296-9492-4803-8a62-f43474474c04.jpg)
| Catalogue Number | 152165 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Cytochrome P450, family 4, subfamily Z, polypeptide 1 (CYP4Z1) |
| Reactivity | Human |
| Relevance | CYP4Z1 was only detected in breast cancer samples (potentially important clinical marker). |
| Host | Mouse |
| Immunogen | Ovalbumin-conjugated synthetic peptide KLAPDHSRPP (C-terminal sequence) |
| Positive Control | ELISA- Peptide immunogen; IHC- formalin-fixed, paraffin-embedded tissue microarrays sections; WB- pooled liver microsomes |
| Subclass | IgG1 kappa |
| Myeloma Used | P3X63Ag8.653 |
| Strain | Balb/c |
| Research Area | Cancer, Cardiovascular, Cell Cycle, Cell Signaling & Signal Transduction, Metabolism |
References: 4 entries
Alnabulsi et al. 2017. Br J Cancer. :. PMID: 28557975.
The differential expression of omega-3 and omega-6 fatty acid metabolising enzymes in colorectal cancer and its prognostic significance.
Europe PMC ID: 28557975
Alnabulsi et al. 2016. Characterisation of Arachidonic Acid Metabolising Enzymes in Colorectal Cancer. J Pathol. 240 Suppl 1:S1-S48. PMID: 27747872
IHC
Nottingham Pathology 2016. 9th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 28 June - 1 July 2016.
Europe PMC ID: 27747872
Add a reference
References: 4 entries
Alnabulsi et al. 2017. Br J Cancer. :. PMID: 28557975.
The differential expression of omega-3 and omega-6 fatty acid metabolising enzymes in colorectal cancer and its prognostic significance.
Alnabulsi et al. 2016. Characterisation of Arachidonic Acid Metabolising Enzymes in Colorectal Cancer. J Pathol. 240 Suppl 1:S1-S48. PMID: 27747872
IHC
Nottingham Pathology 2016. 9th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 28 June - 1 July 2016.
Add a reference
