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Monoclonal Antibodies

Anti-Cytochrome P450 1A1, 1A2 [MC1]

Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
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Catalogue Number 152162
Applications IHC WB
Antigen/Gene or Protein Targets Cytochrome P450 1A1, 1A2 (CYP1A1, CYP1A2)
Reactivity Human
Relevance Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Host Mouse
Immunogen 3-methylcholanthrene induced rat cytochrome P450 proteins
Positive Control IHC: formalin-fixed, paraffin-embedded normal liver sections; western blot: recombinant P450
Subclass IgG1 kappa
Myeloma Used P3X63Ag8.653
Strain Balb/c
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

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