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Anti-Cytochrome P450 2E1 [M12P4H2]

Invented by Ayham Alnabulsi at Vertebrate Antibodies Limited

Info

Catalogue Number 152160
Applications IHC WB
Antigen/Gene or Protein Targets Cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1)
Reactivity Human
Relevance Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.
Host Mouse
Immunogen Ovalbumin-conjugated synthetic peptide HIGFGCIPPR (C-terminal sequence)
Subclass IgG1 lambda
Positive Control IHC: formalin-fixed, paraffin-embedded human liver sections; WB: pooled human liver microsomes
Myeloma Used P3X63Ag8.653
Recommended Growing Conditions Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM plus 60 ml Fetal Bovine Serum plus 3ml L-Glutamine).
Strain Balb/c
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

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