Anti-Cytochrome P450 2A6 [RP1.2B4]

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Inventor Info

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Catalogue Number	152158
Applications	WB
Antigen/Gene or Protein Targets	Cytochrome P450 2A6, CYP2A6
Reactivity	Human
Relevance	Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Possesses low phenacetin O-deethylation activity.
Host	Mouse
Immunogen	Human cytochrome P450 CYP2A6
Positive Control	western blot: Recombinant P450 - 0.49 pmol per lane.
Subclass	IgG1 kappa
Myeloma Used	P3X63Ag8.653
Recommended Growing Conditions	Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM plus 60 ml Fetal Bovine Serum plus 3ml L-Glutamine).
Strain	Balb/c
Research Area	Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

There are 1 reference entries for this reagent.

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Barnes, T. S. (1987). The generation and characterization of monoclonal antibodies to human cytochrome P450. Ph. D. Thesis. University of Aberdeen.

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Barnes, T. S. (1987). The generation and characterization of monoclonal antibodies to human cytochrome P450. Ph. D. Thesis. University of Aberdeen.

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	Ayham Alnabulsi
	from Vertebrate Antibodies Limited Linked to 154 other reagents on Ximbio.

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	Vertebrate Antibodies Limited
	199 reagents listed on Ximbio

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