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Anti-Cytochrome P450 2A6 [RP1.2B4]

Invented by Ayham Alnabulsi at Vertebrate Antibodies Limited

Info

Catalogue Number 152158
Applications WB
Antigen/Gene or Protein Targets Cytochrome P450 2A6, CYP2A6
Reactivity Human
Relevance Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Possesses low phenacetin O-deethylation activity.
Host Mouse
Immunogen Human cytochrome P450 CYP2A6
Subclass IgG1 kappa
Positive Control western blot: Recombinant P450 - 0.49 pmol per lane.
Myeloma Used P3X63Ag8.653
Recommended Growing Conditions Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM plus 60 ml Fetal Bovine Serum plus 3ml L-Glutamine).
Strain Balb/c
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

References: 1 entry

Barnes, T. S. (1987). The generation and characterization of monoclonal antibodies to human cytochrome P450. Ph. D. Thesis. University of Aberdeen.


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References: 1 entry

Barnes, T. S. (1987). The generation and characterization of monoclonal antibodies to human cytochrome P450. Ph. D. Thesis. University of Aberdeen.


Add a reference

References: 1 entry

Barnes, T. S. (1987). The generation and characterization of monoclonal antibodies to human cytochrome P450. Ph. D. Thesis. University of Aberdeen.


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