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Anti-SRp55 [9-1-56]

Info

Applications IHC IP WB
Antigen/Gene or Protein Targets SRp55
Reactivity Human
Relevance Pre-mRNA-splicing factor SRp55 is a member of the serine/arginine-rich (SR) protein family. This group of proteins is found mainly in the nucleus where they play a critical role in regulated and constitutive splicing of precursor mRNAs. SRp55 is involved in the constitutive process for mRNA splicing, and is able to mediate alternative splice site selection. Considered one of the more ubiquitous of the splice factors, SRp55 is upregulated in response to DNA damage when p53 is lacking. SRp55 is significantly phosphorylated on RS domain serine residues.
Host Mouse
Immunogen MBP-tagged recombinant protein corresponding to human SRp55
Subclass IgG1 kappa
Research Area Epigenetics & Nuclear Signalling

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