Anti-caspase-8 [4-1-20]
Invented at Cold Spring Harbor Laboratory
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Info
| Applications | IHC IF IP WB |
| Antigen/Gene or Protein Targets | Caspase 8 |
| Reactivity | Human |
| Relevance | Caspase-8 is a member of the cysteine proteases, which are implicated in the apoptosis and cytokine processing. As with all caspases, caspase-8 is synthesised as an inactive zymogen procaspase, which becomes activated by proteolytic cleavage, through either auto-activation after recruitment into a multimeric complex or trans-cleavage by other caspases. |
| Host | Mouse |
| Immunogen | Full length recombinant human caspase 8 protein |
| Subclass | IgG1 kappa |
| Research Area | Apoptosis and Programmed Cell Death, Cancer, Metabolism, Protein Degradation |
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