Anti-PTP-PEST [AG10]
Invented at Cold Spring Harbor Laboratory
- Datasheet
- References (2)
- Inventor Info
Info
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| Applications | IP WB |
| Antigen/Gene or Protein Targets | PTP-PEST |
| Reactivity | Human, Mouse and Rat |
| Relevance | PTP-PEST is a protein-tyrosine phosphatase which regulates fibroblast adhesion, migration and cytokinesis through its association with and dephosphorylation of p130 Cas, paxillin, PSTPIP1, WASP and other adhesion molecules. PTP-PEST also regulates adhesion and motility of cultured epithelial cells through modulation of Rho GTPase activity and is required for integrin-mediated endothelial cell adhesion and migration. |
| Host | Mouse |
| Immunogen | Human PTP-PEST recombinant protein. |
| Subclass | IgG1 |
| Research Area | Adhesion |
References: 2 entries
Garton et al. 1997. Oncogene. 15(8):877-85. PMID: 9285683.
Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition.
Europe PMC ID: 9285683
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References: 2 entries
Garton et al. 1997. Oncogene. 15(8):877-85. PMID: 9285683.
Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition.
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