Anti-FOXP2 [73A/8]
Invented by Prof Alison Banham from University of Oxford
Invented at University of Oxford
- Datasheet
- References (6)
- Inventor Info
Info
![Image for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/daabfdd1-1555-41e3-90de-ef86af6917e9.jpg)
![Image for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/0414bd3b-11d8-4d63-9b10-eed93f02914e.jpg)
![Image for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/2e76354a-6fc6-4002-9470-2f65e1506105.jpg)
![Image for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/11677b1e-8e3f-4f8f-84be-722215b37aa2.jpg)
![Image for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/4046686c-04bd-4197-905b-5649e0c48b12.jpg)
![Image for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/daabfdd1-1555-41e3-90de-ef86af6917e9.jpg)
![Image for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/0414bd3b-11d8-4d63-9b10-eed93f02914e.jpg)
![Image for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/2e76354a-6fc6-4002-9470-2f65e1506105.jpg)
![Image for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/11677b1e-8e3f-4f8f-84be-722215b37aa2.jpg)
![Image for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/4046686c-04bd-4197-905b-5649e0c48b12.jpg)
![Image thumbnail for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/daabfdd1-1555-41e3-90de-ef86af6917e9.jpg)
![Image thumbnail for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/0414bd3b-11d8-4d63-9b10-eed93f02914e.jpg)
![Image thumbnail for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/2e76354a-6fc6-4002-9470-2f65e1506105.jpg)
![Image thumbnail for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/11677b1e-8e3f-4f8f-84be-722215b37aa2.jpg)
![Image thumbnail for Anti-FOXP2 [73A/8]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/4046686c-04bd-4197-905b-5649e0c48b12.jpg)
| Applications | ChIP IHC WB |
| Antigen/Gene or Protein Targets | FOXP2 |
| Reactivity | Human and Mouse |
| Relevance | FOXP2 is a member of the forkhead transcription factor. Its mutation is associated with an inherited speech and language disorder and its biological roles have primarily been studied in neuronal tissues. FOXP2 is also aberrantly expressed in abnormal plasma cells and it may play a role in the pathogenesis of multiple myeloma. The FOXP2-73A/8 antibody detects human and murine FOXP2 and does not cross-react with other members of the FOXP family (FOXP1, FOXP3 or FOXP4). |
| Immunogen | Bacterially expressed GST-protein containing N-terminus of FOXP2 |
| Subclass | IgG1 |
| Myeloma Used | P3X63Ag8.653 |
| Research Area | Epigenetics & Nuclear Signalling, Neurobiology |
References: 6 entries
FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.
Europe PMC ID: 27224915
Wong et al. 2016. Oncotarget. :. PMID: 27224915.
IHC WB
Gascoyne et al. 2015. PLoS One. 10(6):e0128513. PMID: 26034982.
ChIP IHC
The Forkhead Transcription Factor FOXP2 Is Required for Regulation of p21WAF1/CIP1 in 143B Osteosarcoma Cell Growth Arrest.
Europe PMC ID: 26034982
Campbell et al. 2010. Br J Haematol. 149(2):221-30. PMID: 20096010.
Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells.
Europe PMC ID: 20096010
Add a reference
References: 6 entries
FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.
Wong et al. 2016. Oncotarget. :. PMID: 27224915.
IHC WB
Gascoyne et al. 2015. PLoS One. 10(6):e0128513. PMID: 26034982.
ChIP IHC
The Forkhead Transcription Factor FOXP2 Is Required for Regulation of p21WAF1/CIP1 in 143B Osteosarcoma Cell Growth Arrest.
Campbell et al. 2010. Br J Haematol. 149(2):221-30. PMID: 20096010.
Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells.
Add a reference
