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Anti-FOXP2 [73A/8]

Invented by Prof Alison Banham at University of Oxford

Info

Applications ChIP IHC WB
Antigen/Gene or Protein Targets FOXP2
Reactivity Human and Mouse
Relevance FOXP2 is a member of the forkhead transcription factor. Its mutation is associated with an inherited speech and language disorder and its biological roles have primarily been studied in neuronal tissues. FOXP2 is also aberrantly expressed in abnormal plasma cells and it may play a role in the pathogenesis of multiple myeloma. The FOXP2-73A/8 antibody detects human and murine FOXP2 and does not cross-react with other members of the FOXP family (FOXP1, FOXP3 or FOXP4).
Immunogen Bacterially expressed GST-protein containing N-terminus of FOXP2
Subclass IgG1
Myeloma Used P3X63Ag8.653
Research Area Epigenetics & Nuclear Signalling, Neurobiology

References: 6 entries

Wong et al. 2016. Oncotarget. :. PMID: 27224915.

IHC WB

FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.

Europe PMC ID: 27224915

Gascoyne et al. 2015. PLoS One. 10(6):e0128513. PMID: 26034982.

ChIP IHC

The Forkhead Transcription Factor FOXP2 Is Required for Regulation of p21WAF1/CIP1 in 143B Osteosarcoma Cell Growth Arrest.

Europe PMC ID: 26034982

Campbell et al. 2010. Br J Haematol. 149(2):221-30. PMID: 20096010.

Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells.

Europe PMC ID: 20096010


Add a reference

References: 6 entries

Wong et al. 2016. Oncotarget. :. PMID: 27224915.

IHC WB

FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.

Europe PMC ID: 27224915

Gascoyne et al. 2015. PLoS One. 10(6):e0128513. PMID: 26034982.

ChIP IHC

The Forkhead Transcription Factor FOXP2 Is Required for Regulation of p21WAF1/CIP1 in 143B Osteosarcoma Cell Growth Arrest.

Europe PMC ID: 26034982

Campbell et al. 2010. Br J Haematol. 149(2):221-30. PMID: 20096010.

Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells.

Europe PMC ID: 20096010


Add a reference

References: 6 entries

Wong et al. 2016. Oncotarget. :. PMID: 27224915.

IHC WB

FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.

Gascoyne et al. 2015. PLoS One. 10(6):e0128513. PMID: 26034982.

ChIP IHC

The Forkhead Transcription Factor FOXP2 Is Required for Regulation of p21WAF1/CIP1 in 143B Osteosarcoma Cell Growth Arrest.

Campbell et al. 2010. Br J Haematol. 149(2):221-30. PMID: 20096010.

Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells.


Add a reference


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