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Anti-FOXP1 [JC12]

Info

Applications ChIP IHC WB
Antigen/Gene or Protein Targets FOXP1
Reactivity Mouse
Relevance JC12 has been used in the identification of a novel winged helix transcription factor, FOXP1. The FOXP1 gene has been mapped to chromosome 3p14.1, a chromosomal locus shown to be disrupted in a range of solid tumors. Characterization of both FOXP1 mRNA and protein expression has shown that this molecule is widely expressed in normal tissues, and that its expression is frequently altered in solid tumors.
Host Mouse
Subclass IgG2a
Recommended Growing Conditions RPMI 1640 containing 10% FCS at 37°C in 5% CO2.
Research Area Cancer, Epigenetics & Nuclear Signalling

References: 9 entries

Gascoyne et al. 2016. Endocrinology. :en20161802. PMID: 28001444.

WB

Gascoyne et al. 2016. Leuk Lymphoma. :1-15. PMID: 27678023.

IHC

The significance of FOXP1 in diffuse large B-cell lymphoma.

Europe PMC ID: 27678023

FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.

Europe PMC ID: 27224915

Wong et al. 2016. Oncotarget. :. PMID: 27224915.

IHC WB

Brown et al. 2015. Leukemia. :. PMID: 26500140.

ChIP

FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas.

Europe PMC ID: 26500140

Banham et al. 2001. Cancer Res. 61(24):8820-9. PMID: 11751404.

WB

The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.

Europe PMC ID: 11751404


Add a reference

References: 9 entries

Gascoyne et al. 2016. Endocrinology. :en20161802. PMID: 28001444.

WB

Gascoyne et al. 2016. Leuk Lymphoma. :1-15. PMID: 27678023.

IHC

The significance of FOXP1 in diffuse large B-cell lymphoma.

Europe PMC ID: 27678023

FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.

Europe PMC ID: 27224915

Wong et al. 2016. Oncotarget. :. PMID: 27224915.

IHC WB

Brown et al. 2015. Leukemia. :. PMID: 26500140.

ChIP

FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas.

Europe PMC ID: 26500140

Banham et al. 2001. Cancer Res. 61(24):8820-9. PMID: 11751404.

WB

The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.

Europe PMC ID: 11751404


Add a reference

References: 9 entries

Gascoyne et al. 2016. Endocrinology. :en20161802. PMID: 28001444.

WB

Gascoyne et al. 2016. Leuk Lymphoma. :1-15. PMID: 27678023.

IHC

The significance of FOXP1 in diffuse large B-cell lymphoma.

FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.

Wong et al. 2016. Oncotarget. :. PMID: 27224915.

IHC WB

Brown et al. 2015. Leukemia. :. PMID: 26500140.

ChIP

FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas.

Banham et al. 2001. Cancer Res. 61(24):8820-9. PMID: 11751404.

WB

The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.


Add a reference


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