Anti-MTSS1 [M7P3A7]
Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
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![Image for Anti-MTSS1 [M7P3A7]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/ab31cec5-dc02-4f99-9f19-29f7077c08e9.jpg)
![Immunohistochemistry was performed on formalin-fixed, paraffin-embedded tissue sections. Positive cytoplasmic staining was observed in breast cancer sections using Anti-MTSS1 [M7P3A7]. Antigen retrieval step is required using EDTA buffer, PH8.0.](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/e0af21a4-4ffa-4d8b-8476-8cc1f8ab1fbf.jpg)
![Image for Anti-MTSS1 [M7P3A7]](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/ab31cec5-dc02-4f99-9f19-29f7077c08e9.jpg)
![Immunohistochemistry was performed on formalin-fixed, paraffin-embedded tissue sections. Positive cytoplasmic staining was observed in breast cancer sections using Anti-MTSS1 [M7P3A7]. Antigen retrieval step is required using EDTA buffer, PH8.0.](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/e0af21a4-4ffa-4d8b-8476-8cc1f8ab1fbf.jpg)
![Image thumbnail for Anti-MTSS1 [M7P3A7]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/ab31cec5-dc02-4f99-9f19-29f7077c08e9.jpg)
![Image thumbnail for Anti-MTSS1 [M7P3A7]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/e0af21a4-4ffa-4d8b-8476-8cc1f8ab1fbf.jpg)
| Catalogue Number | 151872 |
| Applications | ELISA IF WB |
| Antigen/Gene or Protein Targets | Metastasis suppressor protein 1 (MTSS1) |
| Reactivity | Human |
| Relevance | Metastasis suppressor protein 1 (MTSS1, MIM) is an actin-binding scaffold protein that has been implicated to play an important role in carcinogenesis and cancer metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton. |
| Host | Mouse |
| Immunogen | Peptide Sequence - KPSIPEEHRQ (amino acids 679 - 688) |
| Positive Control | ELISA- Peptide immunogenWestern Blot- Calu6 cell extract (cytoplasmic fraction)Immunofluorescence- Hela Cells |
| Subclass | IgG1 |
| Myeloma Used | P3X63Ag8.653 |
| Recommended Growing Conditions | Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM + 60 ml Fetal Bovine Serum plus 3ml L-Glutamine + 3ml of Penicillin -Streptomycin. |
| Strain | Balb/c |
| Research Area | Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling |
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