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Anti-Cytochrome P450 3A5 [F18P3B6]

Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited

Info

Catalogue Number 151863
Applications ELISA IHC WB
Antigen/Gene or Protein Targets CYP3A5- Cytochrome P450 3A5 (EC 1.14.14.1) (niphedipine oxidase), (CYPIIIA5) (P450-PCN3) (HLp2).
Reactivity Human
Relevance This monoclonal antibody (MAb), when used in conjunction with the MAb specific to CYP3A7 clone F19 P2 H2, is able to differentiate between the CYP450 family 3 members: CYP3A5 and CYP3A7.
Host Mouse
Immunogen Ovalbumin-conjugated synthetic peptide DSRDGTLSGE (C-terminal sequence)
Positive Control IHC: formalin-fixed, paraffin-embedded squamous oesophagus cancer sections western blot: recombinant P450 (shown below @ 0.5 pmol per lane).
Subclass IgG1 kappa
Myeloma Used P3X63Ag8.653
Strain Balb/c
Notes Recommended usage condition: 1/5 dilution, antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

References

There are 10 reference entries for this reagent.

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References: 10 entries

Zia et al. 2015. Int J Exp Pathol. 96(2):81-6. PMID: 25670065.

CYP3A isoforms in Ewing's sarcoma tumours: an immunohistochemical study with clinical correlation.

Europe PMC ID: 25670065

Murray et al. 2010. Histopathology. 57(2):202-11. PMID: 20716162.

Profiling the expression of cytochrome P450 in breast cancer.

Europe PMC ID: 20716162

Downie et al. 2005. Clin Cancer Res. 11(20):7369-75. PMID: 16243809.

Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers.

Europe PMC ID: 16243809

Kumarakulasingham et al. 2005. Clin Cancer Res. 11(10):3758-65. PMID: 15897573.

IHC WB

Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis.

Europe PMC ID: 15897573

Kosik et al. 1992. Science. 256(5058):780-3. PMID: 1589757.

Alzheimer's disease: a cell biological perspective.

Europe PMC ID: 1589757


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References: 10 entries

Zia et al. 2015. Int J Exp Pathol. 96(2):81-6. PMID: 25670065.

CYP3A isoforms in Ewing's sarcoma tumours: an immunohistochemical study with clinical correlation.

Murray et al. 2010. Histopathology. 57(2):202-11. PMID: 20716162.

Profiling the expression of cytochrome P450 in breast cancer.

Downie et al. 2005. Clin Cancer Res. 11(20):7369-75. PMID: 16243809.

Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers.

Kumarakulasingham et al. 2005. Clin Cancer Res. 11(10):3758-65. PMID: 15897573.

IHC WB

Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis.

Kosik et al. 1992. Science. 256(5058):780-3. PMID: 1589757.

Alzheimer's disease: a cell biological perspective.


Add a reference