Anti-Cytochrome P450 3A5 [F18P3B6]
Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
- Datasheet
- References (10)
- Inventor Info
Info
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| Catalogue Number | 151863 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | CYP3A5- Cytochrome P450 3A5 (EC 1.14.14.1) (niphedipine oxidase), (CYPIIIA5) (P450-PCN3) (HLp2). |
| Reactivity | Human |
| Relevance | This monoclonal antibody (MAb), when used in conjunction with the MAb specific to CYP3A7 clone F19 P2 H2, is able to differentiate between the CYP450 family 3 members: CYP3A5 and CYP3A7. |
| Host | Mouse |
| Immunogen | Ovalbumin-conjugated synthetic peptide DSRDGTLSGE (C-terminal sequence) |
| Positive Control | IHC: formalin-fixed, paraffin-embedded squamous oesophagus cancer sections western blot: recombinant P450 (shown below @ 0.5 pmol per lane). |
| Subclass | IgG1 kappa |
| Myeloma Used | P3X63Ag8.653 |
| Strain | Balb/c |
| Notes | Recommended usage condition: 1/5 dilution, antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0 |
| Research Area | Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism |
References: 10 entries
Zia et al. 2015. Int J Exp Pathol. 96(2):81-6. PMID: 25670065.
CYP3A isoforms in Ewing's sarcoma tumours: an immunohistochemical study with clinical correlation.
Europe PMC ID: 25670065
Murray et al. 2010. Histopathology. 57(2):202-11. PMID: 20716162.
Profiling the expression of cytochrome P450 in breast cancer.
Europe PMC ID: 20716162
Downie et al. 2005. Clin Cancer Res. 11(20):7369-75. PMID: 16243809.
Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers.
Europe PMC ID: 16243809
Kumarakulasingham et al. 2005. Clin Cancer Res. 11(10):3758-65. PMID: 15897573.
IHC WB
Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis.
Europe PMC ID: 15897573
Kosik et al. 1992. Science. 256(5058):780-3. PMID: 1589757.
Alzheimer's disease: a cell biological perspective.
Europe PMC ID: 1589757
Add a reference
References: 10 entries
Zia et al. 2015. Int J Exp Pathol. 96(2):81-6. PMID: 25670065.
CYP3A isoforms in Ewing's sarcoma tumours: an immunohistochemical study with clinical correlation.
Murray et al. 2010. Histopathology. 57(2):202-11. PMID: 20716162.
Profiling the expression of cytochrome P450 in breast cancer.
Downie et al. 2005. Clin Cancer Res. 11(20):7369-75. PMID: 16243809.
Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers.
Kumarakulasingham et al. 2005. Clin Cancer Res. 11(10):3758-65. PMID: 15897573.
IHC WB
Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis.
Kosik et al. 1992. Science. 256(5058):780-3. PMID: 1589757.
Alzheimer's disease: a cell biological perspective.
Add a reference
