Anti-Cytochrome P450 3A4 [F24 P2 B10]

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References (2)

Inventor Info

Info

Catalogue Number	151862
Applications	ELISA IHC WB
Antigen/Gene or Protein Targets	CYP3A4 & CYP3A5 Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine 3-monooxigenase)
Reactivity	Human
Relevance	Cytochrome P450 3A4 (CYP3A4) encodes a member of the cytochrome P450 superfamily of enzymes that are a group of heme-thiolate monooxygenases. Cytochromes P450 catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP3A4 expressed mainly in the liver and intestine oxidizes xebiotics that are then removed from the body.
Host	Mouse
Immunogen	Ovalbumin-conjugated synthetic peptide ESRDGTVSGA
Positive Control	IHC: formalin-fixed, paraffin-embedded prostate cancer sections. Western blot: recombinant P450 (shown below @ 0.5 pmol per lane). Negative control: Gentest Cat. No M101b.
Subclass	IgG1 kappa
Myeloma Used	P3X63Ag8.653
Recommended Growing Conditions	Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM + 60 ml Fetal Bovine Serum plus 3ml L-Glutamine + 3ml of Penicillin -Streptomycin.
Strain	Balb/c
Research Area	Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

There are 2 reference entries for this reagent.

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Murray et al. 2010. Histopathology. 57(2):202-11. PMID: 20716162.

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Profiling the expression of cytochrome P450 in breast cancer.

Europe PMC ID: 20716162

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Murray et al. 2010. Histopathology. 57(2):202-11. PMID: 20716162.

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Profiling the expression of cytochrome P450 in breast cancer.

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	Ayham Alnabulsi
	from Vertebrate Antibodies Limited Linked to 154 other reagents on Ximbio.

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	Vertebrate Antibodies Limited
	199 reagents listed on Ximbio

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