Log in Register
Menu

Anti-Cytochrome P450 3A4 [F24 P2 B10]

Invented by Ayham Alnabulsi at Vertebrate Antibodies Limited

Info

Catalogue Number 151862
Applications ELISA IHC WB
Antigen/Gene or Protein Targets CYP3A4 & CYP3A5 Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine 3-monooxigenase)
Reactivity Human
Relevance Cytochrome P450 3A4 (CYP3A4) encodes a member of the cytochrome P450 superfamily of enzymes that are a group of heme-thiolate monooxygenases. Cytochromes P450 catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP3A4 expressed mainly in the liver and intestine oxidizes xebiotics that are then removed from the body.
Host Mouse
Immunogen Ovalbumin-conjugated synthetic peptide ESRDGTVSGA
Subclass IgG1 kappa
Positive Control IHC: formalin-fixed, paraffin-embedded prostate cancer sections. Western blot: recombinant P450 (shown below @ 0.5 pmol per lane). Negative control: Gentest Cat. No M101b.
Myeloma Used P3X63Ag8.653
Recommended Growing Conditions Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM + 60 ml Fetal Bovine Serum plus 3ml L-Glutamine + 3ml of Penicillin -Streptomycin.
Strain Balb/c
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

References: 1 entry

Murray et al. 2010. Histopathology. 57(2):202-11. PMID: 20716162.


Add a reference

References: 1 entry

Murray et al. 2010. Histopathology. 57(2):202-11. PMID: 20716162.


Add a reference

References: 1 entry

Murray et al. 2010. Histopathology. 57(2):202-11. PMID: 20716162.


Add a reference


This reagent does not have any reviews at the moment.