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Anti-RSV G Glycoprotein [11-2-D2]

Invented by Ayham Alnabulsi at Vertebrate Antibodies Limited

Info

Catalogue Number 151859
Applications ELISA IF Fn WB
Antigen/Gene or Protein Targets Human Respiratory Syncytial (RS) virus G glycoprotein
Synonyms GP90
Reactivity Virus
Relevance Human Respiratory Syncytial Virus (RSV) is a major cause of lower respiratory tract illness and is the chief cause of hospitalization for respiratory tract illness in young children.

The glycoprotein G (also named GP90) is located on the surface of viral envelope, its function is to attach to host cell receptors. It has high content (90%) of carbohydrate.

To our knowledge, this is the only G specific antibody reported to induce in vitro antibody-dependent enhancement of macrophage cells (Clin Diagn Lab Immunol. 1996 May;3(3):280-6).
Host Mouse
Immunogen Gradient-purified RSF-44 virus (subgroup A) UV inactivated for 20 minutes at 20C
Subclass IgG2a kappa
Positive Control WB: Ag: gradient-purified RS virus (see figure). IF: staining of RSA-2 infected BSC-1 cells
Myeloma Used P3X63Ag8.653
Recommended Growing Conditions Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM plus 60 ml Fetal Bovine Serum plus 3ml L-Glutamine).
Strain Balb/c
Notes Antibody reactive with Glycoprotein G of subgroup B
Research Area Virology

References: 3 entries

Gimenez et al. 1996. Clin Diagn Lab Immunol. 3(3):280-6. PMID: 8705669.

Fn

Gimenez et al. 1989. J Gen Virol. 70 ( Pt 1):89-96. PMID: 2732688.

Gimenez et al. 1987. J Gen Virol. 68 ( Pt 5):1267-75. PMID: 3572364.


Add a reference

References: 3 entries

Gimenez et al. 1996. Clin Diagn Lab Immunol. 3(3):280-6. PMID: 8705669.

Fn

Gimenez et al. 1989. J Gen Virol. 70 ( Pt 1):89-96. PMID: 2732688.

Gimenez et al. 1987. J Gen Virol. 68 ( Pt 5):1267-75. PMID: 3572364.


Add a reference

References: 3 entries

Gimenez et al. 1996. Clin Diagn Lab Immunol. 3(3):280-6. PMID: 8705669.

Fn

Gimenez et al. 1989. J Gen Virol. 70 ( Pt 1):89-96. PMID: 2732688.

Gimenez et al. 1987. J Gen Virol. 68 ( Pt 5):1267-75. PMID: 3572364.


Add a reference


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