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Anti-Desmoglein [33-3D]

Info

Catalogue Number 151794
Applications EM IHC IF WB
Antigen/Gene or Protein Targets Desmoglein 1 and 2
Reactivity Bovine and Human
Relevance Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are intercellular adhesive junctions that occur in almost all epithelia and should therefore be useful as epithelial markers in tumour diagnosis. 33-3D is directed against desmoglein in mammalian tissues, tumours and cultured cells.
Host Mouse
Immunogen Bovine desmoglein (desmosomal glycoprotein 1) from nasal epidermis
Subclass IgM
Positive Control 33-3D was validated on MDCK cells which are fixed using methanol (Vilela et al 1995).
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 2mM glutamine + 20% FBS
Strain Balb/c
Research Area Adhesion, Cancer, Cell Signaling & Signal Transduction

References: 12 entries

Krunic et al. 1998. Br J Cancer. 77(8):1275-9. PMID: 9579833.

IHC

Immunohistochemical staining for desmogleins 1 and 2 in keratinocytic neoplasms with squamous phenotype: actinic keratosis, keratoacanthoma and squamous cell carcinoma of the skin.

Europe PMC ID: 9579833

Krunic et al. 1996. Acta Derm Venereol. 76(5):394-8. PMID: 8891017.

IHC

Differential expression of desmosomal glycoproteins in keratoacanthoma and squamous cell carcinoma of the skin: an immunohistochemical aid to diagnosis.

Europe PMC ID: 8891017

Schäfer et al. 1996. Differentiation. 60(2):99-108. PMID: 8641550.

IHC

Immunological identification and characterization of the desmosomal cadherin Dsg2 in coupled and uncoupled epithelial cells and in human tissues.

Europe PMC ID: 8641550

Vilela et al. 1995. J Cell Sci. 108 ( Pt 4):1743-50. PMID: 7615689.

EM

A simple epithelial cell line (MDCK) shows heterogeneity of desmoglein isoforms, one resembling pemphigus vulgaris antigen.

Europe PMC ID: 7615689

Collins et al. 1990. Br J Cancer. 62(5):796-805. PMID: 2123114.

WB

A study of desmosomes in colorectal carcinoma.

Europe PMC ID: 2123114

Vilela et al. 1987. J Pathol. 153(4):365-75. PMID: 3323436.

IHC

Monoclonal antibody to desmosomal glycoprotein 1--a new epithelial marker for diagnostic pathology.

Europe PMC ID: 3323436


Add a reference

References: 12 entries

Krunic et al. 1998. Br J Cancer. 77(8):1275-9. PMID: 9579833.

IHC

Immunohistochemical staining for desmogleins 1 and 2 in keratinocytic neoplasms with squamous phenotype: actinic keratosis, keratoacanthoma and squamous cell carcinoma of the skin.

Europe PMC ID: 9579833

Krunic et al. 1996. Acta Derm Venereol. 76(5):394-8. PMID: 8891017.

IHC

Differential expression of desmosomal glycoproteins in keratoacanthoma and squamous cell carcinoma of the skin: an immunohistochemical aid to diagnosis.

Europe PMC ID: 8891017

Schäfer et al. 1996. Differentiation. 60(2):99-108. PMID: 8641550.

IHC

Immunological identification and characterization of the desmosomal cadherin Dsg2 in coupled and uncoupled epithelial cells and in human tissues.

Europe PMC ID: 8641550

Vilela et al. 1995. J Cell Sci. 108 ( Pt 4):1743-50. PMID: 7615689.

EM

A simple epithelial cell line (MDCK) shows heterogeneity of desmoglein isoforms, one resembling pemphigus vulgaris antigen.

Europe PMC ID: 7615689

Collins et al. 1990. Br J Cancer. 62(5):796-805. PMID: 2123114.

WB

A study of desmosomes in colorectal carcinoma.

Europe PMC ID: 2123114

Vilela et al. 1987. J Pathol. 153(4):365-75. PMID: 3323436.

IHC

Monoclonal antibody to desmosomal glycoprotein 1--a new epithelial marker for diagnostic pathology.

Europe PMC ID: 3323436


Add a reference

References: 12 entries

Krunic et al. 1998. Br J Cancer. 77(8):1275-9. PMID: 9579833.

IHC

Immunohistochemical staining for desmogleins 1 and 2 in keratinocytic neoplasms with squamous phenotype: actinic keratosis, keratoacanthoma and squamous cell carcinoma of the skin.

Krunic et al. 1996. Acta Derm Venereol. 76(5):394-8. PMID: 8891017.

IHC

Differential expression of desmosomal glycoproteins in keratoacanthoma and squamous cell carcinoma of the skin: an immunohistochemical aid to diagnosis.

Schäfer et al. 1996. Differentiation. 60(2):99-108. PMID: 8641550.

IHC

Immunological identification and characterization of the desmosomal cadherin Dsg2 in coupled and uncoupled epithelial cells and in human tissues.

Vilela et al. 1995. J Cell Sci. 108 ( Pt 4):1743-50. PMID: 7615689.

EM

A simple epithelial cell line (MDCK) shows heterogeneity of desmoglein isoforms, one resembling pemphigus vulgaris antigen.

Collins et al. 1990. Br J Cancer. 62(5):796-805. PMID: 2123114.

WB

A study of desmosomes in colorectal carcinoma.

Vilela et al. 1987. J Pathol. 153(4):365-75. PMID: 3323436.

IHC

Monoclonal antibody to desmosomal glycoprotein 1--a new epithelial marker for diagnostic pathology.


Add a reference


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