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Anti-Desmoglein [33-3D]

Info

Catalogue Number 151794
Applications EM IHC IF WB
Antigen/Gene or Protein Targets Desmoglein 1 and 2
Reactivity Bovine and Human
Relevance Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are intercellular adhesive junctions that occur in almost all epithelia and should therefore be useful as epithelial markers in tumour diagnosis. 33-3D is directed against desmoglein in mammalian tissues, tumours and cultured cells.
Host Mouse
Immunogen Bovine desmoglein (desmosomal glycoprotein 1) from nasal epidermis
Subclass IgM
Positive Control 33-3D was validated on MDCK cells which are fixed using methanol (Vilela et al 1995).
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 2mM glutamine + 20% FBS
Strain Balb/c
Research Area Adhesion, Cancer, Cell Signaling & Signal Transduction

References: 6 entries

Krunic et al. 1998. Br J Cancer. 77(8):1275-9. PMID: 9579833.

IHC

Krunic et al. 1996. Acta Derm Venereol. 76(5):394-8. PMID: 8891017.

IHC

Schäfer et al. 1996. Differentiation. 60(2):99-108. PMID: 8641550.

IHC

Vilela et al. 1995. J Cell Sci. 108 ( Pt 4):1743-50. PMID: 7615689.

EM

Collins et al. 1990. Br J Cancer. 62(5):796-805. PMID: 2123114.

WB

Vilela et al. 1987. J Pathol. 153(4):365-75. PMID: 3323436.

IHC


Add a reference

References: 6 entries

Krunic et al. 1998. Br J Cancer. 77(8):1275-9. PMID: 9579833.

IHC

Krunic et al. 1996. Acta Derm Venereol. 76(5):394-8. PMID: 8891017.

IHC

Schäfer et al. 1996. Differentiation. 60(2):99-108. PMID: 8641550.

IHC

Vilela et al. 1995. J Cell Sci. 108 ( Pt 4):1743-50. PMID: 7615689.

EM

Collins et al. 1990. Br J Cancer. 62(5):796-805. PMID: 2123114.

WB

Vilela et al. 1987. J Pathol. 153(4):365-75. PMID: 3323436.

IHC


Add a reference

References: 6 entries

Krunic et al. 1998. Br J Cancer. 77(8):1275-9. PMID: 9579833.

IHC

Krunic et al. 1996. Acta Derm Venereol. 76(5):394-8. PMID: 8891017.

IHC

Schäfer et al. 1996. Differentiation. 60(2):99-108. PMID: 8641550.

IHC

Vilela et al. 1995. J Cell Sci. 108 ( Pt 4):1743-50. PMID: 7615689.

EM

Collins et al. 1990. Br J Cancer. 62(5):796-805. PMID: 2123114.

WB

Vilela et al. 1987. J Pathol. 153(4):365-75. PMID: 3323436.

IHC


Add a reference


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