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Anti-CD68 [Y-2/131/47]

Invented by Dr Jacqueline Cordell from University of Oxford
Invented at University of Oxford

Info

Catalogue Number 151793
Applications WB
Antigen/Gene or Protein Targets CD68
Synonyms CD68 Molecule; CD68 Antigen; Macrophage Antigen CD68; GP110; Scavenger Receptor Class D; Member; Scavenger Receptor Class D; SCARD1; LAMP4
Reactivity Human
Relevance CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. CD68 is a member of a family of hematopoietic mucin-like molecules that includes leukosialin/CD43 and stem cell antigen CD34.
Host Mouse
Immunogen Phytohaemagglutinin-activated peripheral blood mononuclear cells
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT. Ultroser G (**) can be used at 1% if the cells are not growing well.Please note that this cell line has not been weaned out of HAT
Notes Ultroser G can be used at 1% if the cells are not growing well.
Research Area Cell Type or Organelle Marker, Immunology, Stem Cell Biology

References

There are 8 reference entries for this reagent.

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References: 8 entries

Doussis et al. 1993. J Clin Pathol. 46(4):334-6. PMID: 7684403.

CD68 reactivity of non-macrophage derived tumours in cytological specimens.

Europe PMC ID: 7684403

Pulford et al. 1990. Int Immunol. 2(10):973-80. PMID: 2078523.

Distribution of the CD68 macrophage/myeloid associated antigen.

Europe PMC ID: 2078523

Micklem et al. 1989. Br J Haematol. 73(1):6-11. PMID: 2803980.

A human macrophage-associated antigen (CD68) detected by six different monoclonal antibodies.

Europe PMC ID: 2803980

Pulford et al. 1989. J Clin Pathol. 42(4):414-21. PMID: 2654191.

KP1: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections.

Europe PMC ID: 2654191


Add a reference

References: 8 entries

Doussis et al. 1993. J Clin Pathol. 46(4):334-6. PMID: 7684403.

CD68 reactivity of non-macrophage derived tumours in cytological specimens.

Pulford et al. 1990. Int Immunol. 2(10):973-80. PMID: 2078523.

Distribution of the CD68 macrophage/myeloid associated antigen.

Micklem et al. 1989. Br J Haematol. 73(1):6-11. PMID: 2803980.

A human macrophage-associated antigen (CD68) detected by six different monoclonal antibodies.

Pulford et al. 1989. J Clin Pathol. 42(4):414-21. PMID: 2654191.

KP1: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections.


Add a reference