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Anti-CD11C [CD11C-100/D2]

Invented by Dr Jacqueline Cordell at University of Oxford

Info

Catalogue Number 151791
Applications IP WB
Antigen/Gene or Protein Targets CD11C, Integrin, alpha X (complement component 3 receptor 4 subunit). ITGAX
Synonyms Integrin Subunit Alpha X; Leukocyte Adhesion Glycoprotein P150;95 Alpha Chain; Complement Component 3 Receptor 4 Subunit; Leukocyte Adhesion Receptor P150;95; CD11 Antigen-Like Family Member C; CD11C
Reactivity Human
Relevance The integrin alpha X chain protein (CD11c) belongs to the ß2 integrin subfamily. Integrins are cell surface receptors composed of a heterodimer containing an a and ß subunit. CD11c (the a subunit) combines with CD18 (the ß subunit) to form the leukocyte specific integrin inactivated-C3b receptor 41,2. CD11c is known to be expressed on monocytes/macrophages, granulocytes, activated B cells, in spleen and in bone marrow.
Host Mouse
Immunogen Synthetic peptide conjugated to KLH corresponding to the C terminus of human CD11C: ANGQIAPENGTQTPSPPSEK
Subclass IgG2a
Positive Control Human tonsil
Myeloma Used NS0
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Research Area Adhesion, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology

References: 3 entries

Ihanus E, et al., Blood. 2007 109(2):802-10.PMID: 16985175

Ammon et al. 2000. Immunology. 100(3):364-9. PMID: 10929059.

Bilsland et al. 1994. J Immunol. 152(9):4582-9. PMID: 7512600.


Add a reference

References: 3 entries

Ihanus E, et al., Blood. 2007 109(2):802-10.PMID: 16985175

Ammon et al. 2000. Immunology. 100(3):364-9. PMID: 10929059.

Bilsland et al. 1994. J Immunol. 152(9):4582-9. PMID: 7512600.


Add a reference

References: 3 entries

Ihanus E, et al., Blood. 2007 109(2):802-10.PMID: 16985175

Ammon et al. 2000. Immunology. 100(3):364-9. PMID: 10929059.

Bilsland et al. 1994. J Immunol. 152(9):4582-9. PMID: 7512600.


Add a reference


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