Anti-CD19 [LC-1/32/A10]
Invented by Dr Jacqueline Cordell from University of Oxford
Invented at University of Oxford
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 151788 |
| Applications | IHC WB |
| Antigen/Gene or Protein Targets | CD19 |
| Synonyms | CD19 Molecule; B-Lymphocyte Surface Antigen B4; T-Cell Surface Antigen Leu-12; Differentiation Antigen CD19; CD19 Antigen; CVID3; B4 |
| Reactivity | Human |
| Relevance | CD19 is a cell surface molecule expressed on B lymphocytes and follicular dendritic cells. It is expressed by most pre-B cells and by the majority of non-T-cell acute lymphocytic leukaemias and B-cell type chronic lymphocytic leukaemias. CD19 assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. |
| Host | Mouse |
| Immunogen | A synthetic peptide, corresponding to the C-Terminus of CD19. |
| Positive Control | Any human lymphoid tissue or Ramos cell line for CD19 positive and Jurkat for CD19 negative. |
| Subclass | IgG1 kappa |
| Myeloma Used | NS0 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Research Area | Cancer, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology |
References: 4 entries
Carter et al. 1992. Science. 256(5053):105-7. PMID: 1373518.
CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes.
Europe PMC ID: 1373518
Tedder et al. 1989. J Immunol. 143(2):712-7. PMID: 2472450.
Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily.
Europe PMC ID: 2472450
Add a reference
References: 4 entries
Carter et al. 1992. Science. 256(5053):105-7. PMID: 1373518.
CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes.
Tedder et al. 1989. J Immunol. 143(2):712-7. PMID: 2472450.
Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily.
Add a reference
