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Anti-CD19 [LC-1/32/A10]

Invented by Dr Jacqueline Cordell at University of Oxford

Info

Catalogue Number 151788
Applications IHC WB
Antigen/Gene or Protein Targets CD19
Synonyms CD19 Molecule; B-Lymphocyte Surface Antigen B4; T-Cell Surface Antigen Leu-12; Differentiation Antigen CD19; CD19 Antigen; CVID3; B4
Reactivity Human
Relevance CD19 is a cell surface molecule expressed on B lymphocytes and follicular dendritic cells. It is expressed by most pre-B cells and by the majority of non-T-cell acute lymphocytic leukaemias and B-cell type chronic lymphocytic leukaemias. CD19 assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Host Mouse
Immunogen A synthetic peptide, corresponding to the C-Terminus of CD19.
Subclass IgG1 kappa
Positive Control Any human lymphoid tissue or Ramos cell line for CD19 positive and Jurkat for CD19 negative.
Myeloma Used NS0
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Research Area Cancer, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology

References: 2 entries

Carter et al. 1992. Science. 256(5053):105-7. PMID: 1373518.

Tedder et al. 1989. J Immunol. 143(2):712-7. PMID: 2472450.


Add a reference

References: 2 entries

Carter et al. 1992. Science. 256(5053):105-7. PMID: 1373518.

Tedder et al. 1989. J Immunol. 143(2):712-7. PMID: 2472450.


Add a reference

References: 2 entries

Carter et al. 1992. Science. 256(5053):105-7. PMID: 1373518.

Tedder et al. 1989. J Immunol. 143(2):712-7. PMID: 2472450.


Add a reference


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