Anti-Phospho-cdc20 (Thr79) [BT2.1]
Invented by Julian Gannon from The Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151753 |
| Applications | ELISA WB |
| Antigen/Gene or Protein Targets | cdc20 |
| Synonyms | APC/C activator protein CDC20; Cell division control protein 20; YGL116W; Cell Division Cycle 20; P55CDC; CDC20 Cell Division Cycle 20 Homolog; Cell Division Cycle 20 Homolog; BA276H19.3; CDC20A |
| Reactivity | Xenopus laevis |
| Relevance | Cdc20 (fizzy protein) is associated with the activation of the anaphase-promoting complex at the onset of anaphase. Cdc20 is phosphorylated during mitosis so this epitope is a good marker of cell cycle progression |
| Host | Mouse |
| Immunogen | GPKMQGpTPSRAG. pT represents phosphorylated Thr79. |
| Positive Control | Xenopus egg extract |
| Subclass | Not Known |
| Molecular Weight (kDa) | 55 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | 10% FCS |
| Research Area | Cell Cycle |
References: 2 entries
Labit et al. 2012. EMBO J. 31(15):3351-62. PMID: 22713866.
Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C.
Europe PMC ID: 22713866
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References: 2 entries
Labit et al. 2012. EMBO J. 31(15):3351-62. PMID: 22713866.
Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C.
Add a reference
