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|Antigen/Gene or Protein Targets||Keratin 7, 8 in basal, prickle and intermediate cells|
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins
demonstrate tissue and differentiation specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. LdS 65 is useful for studies of epithelial cells and tumour origin.
|Immunogen||Cytoskeletons of the human urothelial RT4 cell line.|
|Recommended Growing Conditions||DMEM + 5% FCS|
|Research Area||Cell Signaling & Signal Transduction|
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