Anti-SIGLEC3 [CD33 1C7/1]
Invented by Prof Paul Crocker from University of Dundee
Invented at University of Oxford
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 151728 |
| Applications | ELISA WB |
| Antigen/Gene or Protein Targets | CD33 |
| Synonyms | Sialic Acid Binding Ig Like Lectin 12; SIGLECL1; SLG 3; Siglec-12; Siglec-L1; S2V |
| Reactivity | Human |
| Relevance | CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells. The protein is also expressed on and a useful marker for peripheral monocytes. It is also useful for distinguishing myelogenous leukaemia cells from lymphoid or erythroid leukaemias. |
| Host | Mouse |
| Immunogen | Extracellular portion of CD33 fused to the Fc portion of human IgG1 |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Research Area | Cancer, Cell Type or Organelle Marker, Immunology, Stem Cell Biology |
References: 4 entries
Taylor et al. 1999. J Biol Chem. 274(17):11505-12. PMID: 10206955.
The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2.
Europe PMC ID: 10206955
Freeman et al. 1995. Blood. 85(8):2005-12. PMID: 7718872.
Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.
Europe PMC ID: 7718872
Add a reference
References: 4 entries
Taylor et al. 1999. J Biol Chem. 274(17):11505-12. PMID: 10206955.
The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2.
Freeman et al. 1995. Blood. 85(8):2005-12. PMID: 7718872.
Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.
Add a reference
