Log in Register
Menu

Anti-Cytochrome P450 3A4, Polyclonal [CYP3A4]

Invented by Prof Roland Wolf at University of Dundee

Info

Catalogue Number 151726
Applications WB
Antigen/Gene or Protein Targets CYP 3A4
Reactivity Human
Relevance This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1.
Host Sheep
Immunogen Purified recombinant human P450s
Positive Control Human Liver Microsomes
Research Area Cardiovascular, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Metabolism

References: 0 entry

There is no reference for this reagent yet, feel free to use the button below to suggest one.

Add a reference

References: 0 entry

There is no reference for this reagent yet, feel free to use the button below to suggest one.

Add a reference

References: 0 entry

There is no reference for this reagent yet, feel free to use the button below to suggest one.

Add a reference


This reagent does not have any reviews at the moment.