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Anti-Desmoglein 1 [32-2B]

Info

Catalogue Number 151720
Applications EM IHC IF WB
Antigen/Gene or Protein Targets Desmoglein 1
Synonyms Cadherin family member 4, CDHF4, Desmoglein-1, Desmosomal glycoprotein 1, DG1, DGI, DSG, DSG1, EPKHE, EPKHIA, Pemphigus foliaceus antigen, PPKS1, SPPK1
Reactivity Bovine and Human
Relevance Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are intercellular adhesive junctions that occur in almost all epithelia and should therefore be useful as epithelial markers in tumour diagnosis. This antibody was tested for its ability to stain epithelia and tumours. 32-2B is a reliable epithelial marker that may have a useful role in diagnostic histopathology.
Host Mouse
Immunogen Bovine desmoglein (desmosomal glycoprotein I) from nasal epidermis
Subclass IgG2a
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 2mM glutamine + 20% Foetal Bovine Serum
Strain Balb/c
Research Area Adhesion, Cancer, Cell Signaling & Signal Transduction

References: 5 entries

Maruani et al. 2008. Am J Clin Pathol. 130(3):369-74. PMID: 18701409.

IHC

Vilela et al. 1995. J Cell Sci. 108 ( Pt 4):1743-50. PMID: 7615689.

IF WB

Harada et al. 1992. Int J Oral Maxillofac Surg. 21(6):346-9. PMID: 1282923.

IHC

Conn et al. 1990. Br J Urol. 65(2):176-80. PMID: 2317652.

IHC

Vilela et al. 1987. J Pathol. 153(4):365-75. PMID: 3323436.

IHC


Add a reference

References: 5 entries

Maruani et al. 2008. Am J Clin Pathol. 130(3):369-74. PMID: 18701409.

IHC

Vilela et al. 1995. J Cell Sci. 108 ( Pt 4):1743-50. PMID: 7615689.

IF WB

Harada et al. 1992. Int J Oral Maxillofac Surg. 21(6):346-9. PMID: 1282923.

IHC

Conn et al. 1990. Br J Urol. 65(2):176-80. PMID: 2317652.

IHC

Vilela et al. 1987. J Pathol. 153(4):365-75. PMID: 3323436.

IHC


Add a reference

References: 5 entries

Maruani et al. 2008. Am J Clin Pathol. 130(3):369-74. PMID: 18701409.

IHC

Vilela et al. 1995. J Cell Sci. 108 ( Pt 4):1743-50. PMID: 7615689.

IF WB

Harada et al. 1992. Int J Oral Maxillofac Surg. 21(6):346-9. PMID: 1282923.

IHC

Conn et al. 1990. Br J Urol. 65(2):176-80. PMID: 2317652.

IHC

Vilela et al. 1987. J Pathol. 153(4):365-75. PMID: 3323436.

IHC


Add a reference


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