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Anti-CLEC9A [397]

Info

Catalogue Number 151704
Applications WB
Antigen/Gene or Protein Targets Mouse DNGR1
Synonyms C-Type Lectin Domain Family 9 Member A; HEEE9341; UNQ9341; DNGR-1; CD370; DNGR1
Reactivity Mouse
Relevance Recognises mouse DNGR-1, also known as CLEC9A, which is a highly specific marker of the CD8a+ and the CD103+ DC subsets, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.
Host Rat
Immunogen RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope
Subclass IgG2a
Positive Control rat IgG2a isotype-matched control mAbs
Myeloma Used Y3.AG.1.2.3
Recommended Growing Conditions RPMI + 10% FCS + Pen + Strep + Glutamine + 2-ME
Research Area Immunology, Stem Cell Biology

References: 6 entries

Joffre et al. 2010. Eur J Immunol. 40(5):1255-65. PMID: 20333625.

Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A.

Europe PMC ID: 20333625

Sancho et al. 2009. Nature. 458(7240):899-903. PMID: 19219027.

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity.

Europe PMC ID: 19219027

Sancho et al. 2008. J Clin Invest. 118(6):2098-110. PMID: 18497879.

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin.

Europe PMC ID: 18497879


Add a reference

References: 6 entries

Joffre et al. 2010. Eur J Immunol. 40(5):1255-65. PMID: 20333625.

Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A.

Europe PMC ID: 20333625

Sancho et al. 2009. Nature. 458(7240):899-903. PMID: 19219027.

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity.

Europe PMC ID: 19219027

Sancho et al. 2008. J Clin Invest. 118(6):2098-110. PMID: 18497879.

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin.

Europe PMC ID: 18497879


Add a reference

References: 6 entries

Joffre et al. 2010. Eur J Immunol. 40(5):1255-65. PMID: 20333625.

Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A.

Sancho et al. 2009. Nature. 458(7240):899-903. PMID: 19219027.

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity.

Sancho et al. 2008. J Clin Invest. 118(6):2098-110. PMID: 18497879.

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin.


Add a reference


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