Anti-RACO1 [5H10]
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151685 |
| Applications | ELISA IP WB |
| Antigen/Gene or Protein Targets | RACO1 |
| Synonyms | Ring Finger Protein 187; RING Domain AP1 Coactivator 1; Protein RNF187; RACO1 |
| Reactivity | Human, Mouse and Rat |
| Relevance | RING-domain-containing protein (RACO-1) is a c-Jun co-activator that is regulated by the MEK signalling pathway. RACO-1 is a molecular link between growth factor signalling and AP-1. RACO-1 depletion reduces cellular proliferation and decreases expression of several growth-associated AP-1 target genes such as cdc2, cyclin D1 and hb-egf. |
| Host | Mouse |
| Immunogen | Single C-terminal immunogenic peptide |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | E4 + 5% FCS |
| Strain | CD1 |
| Research Area | Cell Signaling & Signal Transduction |
References: 2 entries
Davies et al. 2010. Nat Cell Biol. 12(10):963-72. PMID: 20852630.
Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation.
Europe PMC ID: 20852630
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References: 2 entries
Davies et al. 2010. Nat Cell Biol. 12(10):963-72. PMID: 20852630.
Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation.
Add a reference
