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Anti-TAL1 [2TL75]

Invented by Karen Pulford from University of Oxford
Invented at University of Oxford

Info

Catalogue Number 151660
Applications IHC IP
Antigen/Gene or Protein Targets TAL1
Reactivity Human
Relevance TAL-1 is a member of the helix-loop-helix family of transcription factors. Overexpression of the TAL-1 gene is the most common molecular abnormality found in human T cell leukaemia.
Host Mouse
Immunogen Recombinant protein
Subclass IgG1 kappa
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions It is advised that cells are grown in the following medium:RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT. Ultroser G (**) can be used at 1% if the cells are not growing well.
Research Area Cancer, Cell Cycle, Developmental Biology, Epigenetics & Nuclear Signalling, Stem Cell Biology

References

There are 6 reference entries for this reagent.

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References: 6 entries

Delabesse et al. 1998. Br J Haematol. 102(2):449-57. PMID: 9695959.

TAL1 expression does not occur in the majority of T-ALL blasts.

Europe PMC ID: 9695959

Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670.

Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain.

Europe PMC ID: 7756670

Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471.

Expression of TAL-1 proteins in human tissues.

Europe PMC ID: 7833471


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References: 6 entries

Delabesse et al. 1998. Br J Haematol. 102(2):449-57. PMID: 9695959.

TAL1 expression does not occur in the majority of T-ALL blasts.

Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670.

Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain.

Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471.

Expression of TAL-1 proteins in human tissues.


Add a reference