Anti-TAL1 [2TL75]
Invented by Karen Pulford from University of Oxford
Invented at University of Oxford
- Datasheet
- References (6)
- Inventor Info
Info
| Catalogue Number | 151660 |
| Applications | IHC IP |
| Antigen/Gene or Protein Targets | TAL1 |
| Reactivity | Human |
| Relevance | TAL-1 is a member of the helix-loop-helix family of transcription factors. Overexpression of the TAL-1 gene is the most common molecular abnormality found in human T cell leukaemia. |
| Host | Mouse |
| Immunogen | Recombinant protein |
| Subclass | IgG1 kappa |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | It is advised that cells are grown in the following medium:RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT. Ultroser G (**) can be used at 1% if the cells are not growing well. |
| Research Area | Cancer, Cell Cycle, Developmental Biology, Epigenetics & Nuclear Signalling, Stem Cell Biology |
References: 6 entries
Delabesse et al. 1998. Br J Haematol. 102(2):449-57. PMID: 9695959.
TAL1 expression does not occur in the majority of T-ALL blasts.
Europe PMC ID: 9695959
Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670.
Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain.
Europe PMC ID: 7756670
Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471.
Expression of TAL-1 proteins in human tissues.
Europe PMC ID: 7833471
Add a reference
References: 6 entries
Delabesse et al. 1998. Br J Haematol. 102(2):449-57. PMID: 9695959.
TAL1 expression does not occur in the majority of T-ALL blasts.
Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670.
Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain.
Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471.
Expression of TAL-1 proteins in human tissues.
Add a reference
