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ATF2 Mouse

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Catalogue Number 151648
Antigen/Gene or Protein Targets ATF2
Relevance Alanine substitutions of phosphor acceptor sites T51, T53 (equivalent to human T69, T71). Transcription factor (BZIP-type, AP1-family)
Production Details Atf2 genomic sequences were isolated by screening a 129/ola mouse cosmid library (RZPD), cloned into pPGKneobpAlox2PGKDTA, transfected into 129/ola embryonic stem cells. Transgenic animals were produced by blastocyst injection and offspring mice were backcrossed at least six times with C57 Bl/6 mice to produce isogenic lines.
Conditional No
Growth/Phenotype Keywords Homozygous postnatal lethality, heterozygous normal phenotype
Mouse Genetic Background/Cross History C57 Bl/6
Zygosity Heterozygous
Research Area Cell Cycle, Cell Signaling & Signal Transduction, Developmental Biology, Epigenetics & Nuclear Signalling, Genetic Studies Tools, Immunology

References: 1 entry

Breitwieser et al. 2007. Genes Dev. 21(16):2069-82. PMID: 17699753.


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References: 1 entry

Breitwieser et al. 2007. Genes Dev. 21(16):2069-82. PMID: 17699753.


Add a reference

References: 1 entry

Breitwieser et al. 2007. Genes Dev. 21(16):2069-82. PMID: 17699753.


Add a reference


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