Cancer Research Technology
Log in Register
Menu

Anti-RSV F Glycoprotein [5A6]

Info

Catalogue Number 151637
Applications ELISA IHC IF WB
Antigen/Gene or Protein Targets Respiratory syncytial virus subgroup A G glycoprotein
Reactivity Virus
Relevance RSV5A6 may be used for the detection of the fusion glycoprotein of HRSV of both sub-groups A and B.
Host Mouse
Immunogen hRSV strain A2 infected HeLa cells
Positive Control Human RSV A2 infected HeLa cells
Subclass IgG2a
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI + 10% FCS + Hepes (25mM) + glutamine (2mM)
Notes Reactivity: Respiratory Syncytial Virus
The antibody (IgG2a) was raised against the A2 strain of virus and shown to react in ELISA against a panel of sub-group A strains isolated in Newcastle upon Tyne between 1966 and 1991, and sub-group B strains isolated between 1966 and 1985 as well as the laboratory A strain A2 and B strain 8/60.

Epitope is less defined. As well as ELISA the antibody binds the F (specifically the F1) polypeptide in Western blots. It also binds to the F polypeptide expressed in E. coli but not to any of a set of overlapping fragment of F similarly expressed.
Research Area Virology

References

There are 4 reference entries for this reagent.

View All References

References: 4 entries

Wright et al. 1997. J Pathol. 182(2):238-44. PMID: 9274537.

A monoclonal antibody pool for routine immunohistochemical detection of human respiratory syncytial virus antigens in formalin-fixed, paraffin-embedded tissue.

Europe PMC ID: 9274537

West et al. 1994. J Gen Virol. 75 ( Pt 10):2813-9. PMID: 7931172.

Biological activity, binding site and affinity of monoclonal antibodies to the fusion protein of respiratory syncytial virus.

Europe PMC ID: 7931172


Add a reference

References: 4 entries

Wright et al. 1997. J Pathol. 182(2):238-44. PMID: 9274537.

A monoclonal antibody pool for routine immunohistochemical detection of human respiratory syncytial virus antigens in formalin-fixed, paraffin-embedded tissue.

West et al. 1994. J Gen Virol. 75 ( Pt 10):2813-9. PMID: 7931172.

Biological activity, binding site and affinity of monoclonal antibodies to the fusion protein of respiratory syncytial virus.


Add a reference

Inventor Information

No inventors are currently linked to this reagent.

Add an inventor