Anti-MMP2 [4D3]
Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
- Datasheet
- References (10)
- Inventor Info
Info
Catalogue Number | 151619 |
Applications | ELISA IHC IF IP WB |
Antigen/Gene or Protein Targets | Human matrix metalloproteinase 2 (MMP-2) |
Reactivity | Human |
Relevance | MMP2 degrades type IV collagen and plays an important role in menstrual break down, regulation of vascularization, angiogenesis, and inflammatory response. Mutations of MMP2 are associated with Torg-Winchester syndrome. |
Host | Mouse |
Immunogen | Ovalbumin-conjugated synthetic peptide; TSLGLPPDVQRVD |
Positive Control | IHC: formalin-fixed, paraffin-embedded lung containing intra-alveolar macrophageswestern blot: rhMMP-2, 400 ng per lane |
Subclass | IgG1 |
Myeloma Used | P3X63Ag8.653 |
Strain | Balb/c |
Notes | Does not cross react on Western blot: with MMP-1, -9. The antibody reacts with MMP3 |
Research Area | Adhesion, Cancer, Cardiovascular, Epigenetics & Nuclear Signalling, Metabolism |
References: 10 entries
Jeffery et al. 2009. Histopathology. 54(7):820-8. PMID: 19635101.
The matrix metalloproteinase/tissue inhibitor of matrix metalloproteinase profile in colorectal polyp cancers.
Europe PMC ID: 19635101
Lyall et al. 2006. Clin Cancer Res. 12(4):1184-91. PMID: 16489072.
Profiling markers of prognosis in colorectal cancer.
Europe PMC ID: 16489072
Curran et al. 2004. Clin Cancer Res. 10(24):8229-34. PMID: 15623598.
Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers.
Europe PMC ID: 15623598
Murray et al. 1998. Gut. 43(6):791-7. PMID: 9824606.
Matrix metalloproteinases and their inhibitors in gastric cancer.
Europe PMC ID: 9824606
Murray et al. 1998. J Pathol. 185(3):256-61. PMID: 9771478.
Matrix metalloproteinase-1 is associated with poor prognosis in oesophageal cancer.
Europe PMC ID: 9771478
Add a reference
References: 10 entries
Jeffery et al. 2009. Histopathology. 54(7):820-8. PMID: 19635101.
The matrix metalloproteinase/tissue inhibitor of matrix metalloproteinase profile in colorectal polyp cancers.
Lyall et al. 2006. Clin Cancer Res. 12(4):1184-91. PMID: 16489072.
Profiling markers of prognosis in colorectal cancer.
Curran et al. 2004. Clin Cancer Res. 10(24):8229-34. PMID: 15623598.
Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers.
Murray et al. 1998. Gut. 43(6):791-7. PMID: 9824606.
Matrix metalloproteinases and their inhibitors in gastric cancer.
Murray et al. 1998. J Pathol. 185(3):256-61. PMID: 9771478.
Matrix metalloproteinase-1 is associated with poor prognosis in oesophageal cancer.
Add a reference