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Anti-Pinin, Polyclonal [Pinin]


Catalogue Number 151617
Applications ELISA IHC IF IP WB
Antigen/Gene or Protein Targets Pinin
Reactivity Human
Relevance Pinin is a cell adhesion-associated and nuclear protein that has been shown to localize in the vicinity of intermediate filament (IF) convergence upon the cytoplasmic face of the desmosomal plaque as well as in the nucleus. Some data suggest that pinin may play a role in epithelial cell adhesion and the IF complex through a direct interaction with the keratin filaments. Pinin has also been reported to have a role in RNA processing and transcriptional regulation and is part of the SNARP complex. Together with SNIP1 and other proteins Pinin has a role in regulation of proliferation and cancer.
Host Rabbit
Immunogen Recombinant his-tagged protein
Positive Control U2OS cells
Research Area Cancer, Epigenetics & Nuclear Signalling

References: 1 entry

Bracken et al. 2008. Cancer Res. 68(18):7621-8. PMID: 18794151.

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