- Datasheet
- References (6)
- Inventor Info
Info
| Catalogue Number | 151548 |
| Applications | ChIP ELISA IHC IF IP WB |
| Antigen/Gene or Protein Targets | SNAIL1 |
| Reactivity | Human |
| Relevance | The Snail superfamily are zinc finger transcription factors. Overexpression of Snail1 can lead to cells undergoing EMT (epithelial to mesenchymal transition). This is achieved as Snail1 represses expression of E-cadherin, desmoplakin, muc-1, cytokeratin18 while enhances expression of vimentin and fibronectin. Snail1 therefore has a strong association with metastatic disease. |
| Host | Mouse |
| Immunogen | Human Snail 1 recombinant protein |
| Positive Control | MDAMB-453; MDAMB-435; MDAMB-231; A375 |
| Subclass | IgG2a kappa |
| Research Area | Cancer, Cardiovascular, Epigenetics & Nuclear Signalling |
References: 6 entries
Yang et al. 2018. Exp Mol Med. 50(1):e420. PMID: 29303507.
Goldman et al. 2016. Stem Cell Res. 17(1):62-8. PMID: 27240252.
ChIP
Ju et al. 2015. Cell Death Dis. 6:e1801. PMID: 26136074.
WB
Tuhkanen et al. 2009. BMC Cancer. 9:289. PMID: 19695091.
Vincent et al. 2009. Nat Cell Biol. 11(8):943-50. PMID: 19597490.
Francí et al. 2006. Oncogene. 25(37):5134-44. PMID: 16568079.
Add a reference
References: 6 entries
Yang et al. 2018. Exp Mol Med. 50(1):e420. PMID: 29303507.
Goldman et al. 2016. Stem Cell Res. 17(1):62-8. PMID: 27240252.
ChIP
Ju et al. 2015. Cell Death Dis. 6:e1801. PMID: 26136074.
WB
Tuhkanen et al. 2009. BMC Cancer. 9:289. PMID: 19695091.
Vincent et al. 2009. Nat Cell Biol. 11(8):943-50. PMID: 19597490.
Francí et al. 2006. Oncogene. 25(37):5134-44. PMID: 16568079.
Add a reference
Inventor Information
Inventors
|
Melanie Hardman |
