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Anti-Rheb [Rheb 3H6]


Catalogue Number 151544
Applications IP WB
Antigen/Gene or Protein Targets Rheb
Reactivity Human
Relevance Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP binding proteins. Rheb is expressed at high levels in the brain, but is also found in many other tissues, and can be induced by growth factor stimulation. Rheb triggers activation of the Raf-MEK-MAPK pathway and has an important role in regulating the insulin/Target of rapamycin (TOR) signalling pathway.
Host Mouse
Immunogen Human Rheb GST fusion
Subclass IgG1
Recommended Growing Conditions DMEM + 5%FCS
Notes Suggested Dilutions:
Western blot: 1ug/ml

Immunoprecipitation: 5ug/ml
Research Area Cancer, Cell Signaling & Signal Transduction, Metabolism

References: 1 entry

Findlay et al. 2007. Biochem J. 403(1):13-20. PMID: 17253963.

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