Anti-Factor VII [RFF-VII/2]
Invented by Prof Alison Goodall from University Of Leicester
Invented at University College London
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 151532 |
| Applications | ELISA Fn WB |
| Antigen/Gene or Protein Targets | Factor VII |
| Reactivity | Human |
| Relevance | Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesised in the liver. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa via cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts prothrombin to thrombin. This monoclonal antibody inhibits human FVII activity and may also be used to immunodeplete FVII from normal plasma. |
| Host | Mouse |
| Immunogen | Purified human Factor VII |
| Subclass | IgG1 kappa |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI + 10% FCS; non-adherent; subculture every 2-3 days; split 1:5 |
| Research Area | Cardiovascular |
References: 4 entries
Takase et al. 1988. J Clin Pathol. 41(3):342-5. PMID: 3360958.
Takase et al. 1988. J Clin Pathol. 41(3):337-41. PMID: 3360957.
Monoclonal antibodies to human factor VII: production of immunodepleted plasma for VII:C assays.
Europe PMC ID: 3360958
Monoclonal antibodies to human factor VII: a one step immunoradiometric assay for VII:Ag.
Europe PMC ID: 3360957
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References: 4 entries
Takase et al. 1988. J Clin Pathol. 41(3):342-5. PMID: 3360958.
Takase et al. 1988. J Clin Pathol. 41(3):337-41. PMID: 3360957.
Monoclonal antibodies to human factor VII: production of immunodepleted plasma for VII:C assays.
Monoclonal antibodies to human factor VII: a one step immunoradiometric assay for VII:Ag.
Add a reference
Inventor Information
Inventors
|
Prof Alison Goodall |
