Cancer Research Technology
Log in Register
Menu

Anti-Factor VII [RFF-VII/2]

Invented by Prof Alison Goodall from University Of Leicester
Invented at University College London

Info

Catalogue Number 151532
Applications ELISA Fn WB
Antigen/Gene or Protein Targets Factor VII
Reactivity Human
Relevance Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesised in the liver. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa via cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts prothrombin to thrombin. This monoclonal antibody inhibits human FVII activity and may also be used to immunodeplete FVII from normal plasma.
Host Mouse
Immunogen Purified human Factor VII
Subclass IgG1 kappa
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI + 10% FCS; non-adherent; subculture every 2-3 days; split 1:5
Research Area Cardiovascular

References

There are 4 reference entries for this reagent.

View All References

References: 4 entries

Takase et al. 1988. J Clin Pathol. 41(3):342-5. PMID: 3360958.

Takase et al. 1988. J Clin Pathol. 41(3):337-41. PMID: 3360957.

Monoclonal antibodies to human factor VII: production of immunodepleted plasma for VII:C assays.

Europe PMC ID: 3360958

Monoclonal antibodies to human factor VII: a one step immunoradiometric assay for VII:Ag.

Europe PMC ID: 3360957


Add a reference

References: 4 entries

Takase et al. 1988. J Clin Pathol. 41(3):342-5. PMID: 3360958.

Takase et al. 1988. J Clin Pathol. 41(3):337-41. PMID: 3360957.

Monoclonal antibodies to human factor VII: production of immunodepleted plasma for VII:C assays.

Monoclonal antibodies to human factor VII: a one step immunoradiometric assay for VII:Ag.


Add a reference

Inventor Information